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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
32.73
Human Site:
S829
Identified Species:
60
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
S829
E
E
L
K
K
S
E
S
F
N
R
L
L
E
L
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
S895
E
E
I
K
K
S
K
S
F
S
K
L
L
E
L
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
S829
E
E
L
K
K
S
E
S
F
N
R
L
L
E
L
Dog
Lupus familis
XP_857344
981
113022
S704
E
E
I
K
K
S
K
S
F
S
K
L
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
G814
E
E
I
K
K
S
K
G
F
S
K
L
L
E
L
Rat
Rattus norvegicus
XP_001066898
1064
121036
S822
E
E
L
K
K
S
E
S
F
N
R
L
L
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
S832
E
E
L
K
K
S
D
S
F
T
K
L
L
E
L
Chicken
Gallus gallus
XP_417020
1172
133968
S816
E
E
I
K
K
S
K
S
F
S
K
L
L
E
L
Frog
Xenopus laevis
Q6NTV6
1099
121463
R816
D
D
I
I
S
S
H
R
L
P
L
F
C
Q
L
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
T703
L
R
I
L
D
A
K
T
A
Q
N
L
S
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
K802
E
E
I
R
N
S
K
K
F
S
K
I
L
E
L
Honey Bee
Apis mellifera
XP_395654
1140
128906
K792
E
E
V
K
D
S
K
K
F
A
R
I
L
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
S851
E
E
L
K
H
S
K
S
F
N
K
L
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
73.3
100
73.3
N.A.
66.6
100
N.A.
80
73.3
13.3
6.6
N.A.
46.6
60
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
100
40
33.3
N.A.
86.6
80
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
8
0
0
16
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
85
85
0
0
0
0
24
0
0
0
0
0
0
85
0
% E
% Phe:
0
0
0
0
0
0
0
0
85
0
0
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
54
8
0
0
0
0
0
0
0
16
0
8
0
% I
% Lys:
0
0
0
77
62
0
62
16
0
0
54
0
0
0
0
% K
% Leu:
8
0
39
8
0
0
0
0
8
0
8
77
85
0
93
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
31
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
31
0
0
0
0
% R
% Ser:
0
0
0
0
8
93
0
62
0
39
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _