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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH2 All Species: 9.7
Human Site: S9 Identified Species: 17.78
UniProt: O60879 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60879 NP_006720.1 1101 125569 S9 E Q P G A A A S G A G G G S E
Chimpanzee Pan troglodytes XP_509808 1253 142880 A86 G T P Y P S S A S L R G C R E
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 S9 E Q P G A A A S G A G G G S E
Dog Lupus familis XP_857344 981 113022 R12 E D K K A P L R E K D F S I K
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 L9 E R H R A R A L G R D S K S S
Rat Rattus norvegicus XP_001066898 1064 121036 A11 P G A A A S G A G G G G G G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 S31 W P T T M R S S V R N P N L N
Chicken Gallus gallus XP_417020 1172 133968 S10 S R R P R P R S P P G R G G R
Frog Xenopus laevis Q6NTV6 1099 121463 T9 S L T E G A H T K W G V L K Q
Zebra Danio Brachydanio rerio XP_683813 932 105075 D10 Q Q A A G G E D P N K P S K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 S9 S R H E K T K S T G G G L L D
Honey Bee Apis mellifera XP_395654 1140 128906 S8 M A N R K D K S S T G F L D T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 I43 T P P Q V T V I K D E G N T N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.2 98.4 53 N.A. 53.2 82.1 N.A. 79.2 54.8 21.4 60.6 N.A. 40.8 41.6 N.A. 34.4
Protein Similarity: 100 68.2 99.5 70.5 N.A. 71.2 88.2 N.A. 87.6 71.6 41.2 72.1 N.A. 61 61.4 N.A. 53
P-Site Identity: 100 20 100 13.3 N.A. 33.3 40 N.A. 6.6 20 13.3 6.6 N.A. 20 13.3 N.A. 13.3
P-Site Similarity: 100 40 100 20 N.A. 40 53.3 N.A. 13.3 26.6 26.6 20 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 16 39 24 24 16 0 16 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 8 0 0 0 8 0 8 0 8 16 0 0 8 8 % D
% Glu: 31 0 0 16 0 0 8 0 8 0 8 0 0 0 31 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % F
% Gly: 8 8 0 16 16 8 8 0 31 16 54 47 31 16 0 % G
% His: 0 0 16 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 0 8 8 16 0 16 0 16 8 8 0 8 16 16 % K
% Leu: 0 8 0 0 0 0 8 8 0 8 0 0 24 16 0 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 8 8 0 16 0 16 % N
% Pro: 8 16 31 8 8 16 0 0 16 8 0 16 0 0 0 % P
% Gln: 8 24 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 24 8 16 8 16 8 8 0 16 8 8 0 8 8 % R
% Ser: 24 0 0 0 0 16 16 47 16 0 0 8 16 24 8 % S
% Thr: 8 8 16 8 0 16 0 8 8 8 0 0 0 8 8 % T
% Val: 0 0 0 0 8 0 8 0 8 0 0 8 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _