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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH2 All Species: 26.36
Human Site: T1053 Identified Species: 48.33
UniProt: O60879 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60879 NP_006720.1 1101 125569 T1053 I N K E G D E T G V M D N L L
Chimpanzee Pan troglodytes XP_509808 1253 142880 T1119 M K T E G D E T G V M D N L L
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 T1053 I N K E G D E T G V M D N L L
Dog Lupus familis XP_857344 981 113022 T928 M K T E G D E T G V M D S L L
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 T1038 M K T E G D E T G V M D S L L
Rat Rattus norvegicus XP_001066898 1064 121036 K1024 L E R Q K K K K Q L I D I N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 T1056 M N K E G D E T G V M D N L L
Chicken Gallus gallus XP_417020 1172 133968 T1040 M K T E G E E T G V M D S L L
Frog Xenopus laevis Q6NTV6 1099 121463 G1033 G A A K L E E G C I I D D L L
Zebra Danio Brachydanio rerio XP_683813 932 105075 S895 Q A A R T T P S L L V T S L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 E1026 M D A P Q T Q E G V M D S L L
Honey Bee Apis mellifera XP_395654 1140 128906 E1016 M N A H E T Q E G V M D S L M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 E1064 M T I D D D Q E G V M D N L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.2 98.4 53 N.A. 53.2 82.1 N.A. 79.2 54.8 21.4 60.6 N.A. 40.8 41.6 N.A. 34.4
Protein Similarity: 100 68.2 99.5 70.5 N.A. 71.2 88.2 N.A. 87.6 71.6 41.2 72.1 N.A. 61 61.4 N.A. 53
P-Site Identity: 100 80 100 73.3 N.A. 73.3 6.6 N.A. 93.3 66.6 26.6 6.6 N.A. 40 40 N.A. 46.6
P-Site Similarity: 100 86.6 100 86.6 N.A. 86.6 46.6 N.A. 100 86.6 60 33.3 N.A. 66.6 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 31 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 8 54 0 0 0 0 0 93 8 0 0 % D
% Glu: 0 8 0 54 8 16 62 24 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 54 0 0 8 77 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 8 0 0 0 0 0 0 8 16 0 8 0 8 % I
% Lys: 0 31 24 8 8 8 8 8 0 0 0 0 0 0 8 % K
% Leu: 8 0 0 0 8 0 0 0 8 16 0 0 0 93 70 % L
% Met: 62 0 0 0 0 0 0 0 0 0 77 0 0 0 8 % M
% Asn: 0 31 0 0 0 0 0 0 0 0 0 0 39 8 0 % N
% Pro: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 8 8 0 24 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 0 0 0 0 0 8 0 0 0 0 47 0 0 % S
% Thr: 0 8 31 0 8 24 0 54 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 77 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _