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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
13.03
Human Site:
Y440
Identified Species:
23.89
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
Y440
L
L
I
R
N
D
Y
Y
I
R
P
Q
Y
Y
K
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
F513
L
L
I
R
N
D
N
F
I
R
Q
Q
Y
F
K
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
Y440
L
L
I
R
N
D
Y
Y
I
R
P
Q
Y
Y
K
Dog
Lupus familis
XP_857344
981
113022
Q377
F
V
D
T
C
I
D
Q
A
K
L
E
E
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
F431
L
L
I
R
N
D
R
F
I
R
E
Q
Y
F
K
Rat
Rattus norvegicus
XP_001066898
1064
121036
Y442
L
L
I
R
N
D
Y
Y
I
R
P
Q
Y
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
F462
L
L
I
R
N
D
Y
F
V
R
P
Q
Y
Y
K
Chicken
Gallus gallus
XP_417020
1172
133968
F424
L
L
I
R
N
D
Y
F
I
R
P
Q
Y
F
K
Frog
Xenopus laevis
Q6NTV6
1099
121463
P467
L
P
G
T
E
L
S
P
P
P
P
G
M
V
A
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
S410
G
S
E
P
Y
F
L
S
I
L
Q
H
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
Y407
L
Y
I
R
D
D
F
Y
F
R
P
A
Y
Y
Q
Honey Bee
Apis mellifera
XP_395654
1140
128906
L390
L
F
V
R
D
D
A
L
V
R
P
A
Y
Y
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
F520
D
E
H
R
E
D
D
F
E
E
P
Q
Y
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
73.3
100
0
N.A.
73.3
100
N.A.
86.6
86.6
13.3
6.6
N.A.
60
53.3
N.A.
40
P-Site Similarity:
100
86.6
100
33.3
N.A.
86.6
100
N.A.
100
100
13.3
6.6
N.A.
80
73.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
16
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
16
77
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
16
0
0
0
8
8
8
8
8
0
8
% E
% Phe:
8
8
0
0
0
8
8
39
8
0
0
0
0
39
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
62
0
0
8
0
0
54
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
70
% K
% Leu:
77
54
0
0
0
8
8
8
0
8
8
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
54
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
8
8
8
70
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
16
62
0
0
8
% Q
% Arg:
0
0
0
77
0
0
8
0
0
70
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
0
0
0
16
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
39
31
0
0
0
0
77
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _