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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
36.06
Human Site:
Y972
Identified Species:
66.11
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
Y972
H
N
N
M
M
K
L
Y
E
N
L
G
E
Y
F
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
Y1038
H
E
N
M
E
K
L
Y
Q
S
I
M
G
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
Y972
H
N
N
M
M
K
L
Y
E
N
L
G
E
Y
F
Dog
Lupus familis
XP_857344
981
113022
Y847
H
E
N
M
E
K
L
Y
Q
S
V
M
G
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
Y957
L
G
S
M
T
Q
L
Y
Q
S
I
M
G
Y
Y
Rat
Rattus norvegicus
XP_001066898
1064
121036
Y955
H
S
N
M
L
K
L
Y
E
S
L
G
E
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
Y975
H
N
T
M
T
K
L
Y
E
N
L
G
D
Y
F
Chicken
Gallus gallus
XP_417020
1172
133968
Y959
H
E
N
M
E
K
L
Y
Q
N
V
M
G
Y
Y
Frog
Xenopus laevis
Q6NTV6
1099
121463
K953
L
T
D
I
S
Q
K
K
V
K
L
A
D
Y
L
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
Y833
M
V
L
L
V
G
N
Y
M
N
S
G
S
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
Y945
Q
L
Q
M
E
K
L
Y
K
D
L
S
E
Y
Y
Honey Bee
Apis mellifera
XP_395654
1140
128906
Y935
F
K
N
M
D
S
L
Y
T
E
I
S
E
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
Y983
Y
S
Q
M
K
E
L
Y
T
K
I
A
E
F
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
46.6
100
46.6
N.A.
26.6
80
N.A.
80
53.3
13.3
20
N.A.
46.6
40
N.A.
26.6
P-Site Similarity:
100
73.3
100
73.3
N.A.
66.6
100
N.A.
86.6
73.3
40
33.3
N.A.
66.6
53.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
8
0
0
16
0
0
% D
% Glu:
0
24
0
0
31
8
0
0
31
8
0
0
47
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
39
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
39
31
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
31
0
0
0
0
% I
% Lys:
0
8
0
0
8
62
8
8
8
16
0
0
0
0
0
% K
% Leu:
16
8
8
8
8
0
85
0
0
0
47
0
0
0
8
% L
% Met:
8
0
0
85
16
0
0
0
8
0
0
31
0
0
0
% M
% Asn:
0
24
54
0
0
0
8
0
0
39
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
16
0
0
16
0
0
31
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
16
8
0
8
8
0
0
0
31
8
16
8
0
0
% S
% Thr:
0
8
8
0
16
0
0
0
16
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
8
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
93
0
0
0
0
0
77
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _