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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP20
All Species:
19.39
Human Site:
S298
Identified Species:
53.33
UniProt:
O60882
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60882
NP_004762.2
483
54360
S298
S
I
P
D
L
C
D
S
S
S
S
F
D
A
V
Chimpanzee
Pan troglodytes
XP_001153208
483
54252
S298
S
I
P
D
L
C
D
S
S
S
S
F
D
A
V
Rhesus Macaque
Macaca mulatta
XP_001097602
483
54250
S298
S
T
P
D
L
C
D
S
S
S
S
F
D
A
V
Dog
Lupus familis
XP_854639
483
53792
S298
S
I
P
D
L
C
D
S
S
S
S
F
D
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P57748
482
54355
S297
S
I
P
D
L
C
D
S
S
S
S
F
D
A
V
Rat
Rattus norvegicus
P07152
476
54203
V298
P
A
L
S
F
D
A
V
T
M
L
R
G
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509903
471
53417
T294
N
L
S
L
D
A
I
T
E
L
R
G
E
M
M
Chicken
Gallus gallus
XP_417175
496
56924
P311
E
R
P
E
D
C
D
P
H
L
T
F
D
A
I
Frog
Xenopus laevis
Q10835
469
53622
E293
L
S
I
D
A
I
T
E
L
R
G
E
K
M
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.2
87.5
N.A.
89
43.8
N.A.
45.1
45.1
43.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97.9
92.9
N.A.
94
61.9
N.A.
62.3
63
63.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
0
N.A.
0
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
6.6
N.A.
33.3
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
12
12
0
0
0
0
0
0
67
0
% A
% Cys:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
67
23
12
67
0
0
0
0
0
67
0
0
% D
% Glu:
12
0
0
12
0
0
0
12
12
0
0
12
12
12
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
67
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
12
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
45
12
0
0
12
12
0
0
0
0
0
0
0
23
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
12
12
12
56
0
0
0
12
23
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
23
12
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
67
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
12
12
12
0
0
0
% R
% Ser:
56
12
12
12
0
0
0
56
56
56
56
0
0
0
0
% S
% Thr:
0
12
0
0
0
0
12
12
12
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _