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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPHN1 All Species: 10.3
Human Site: S626 Identified Species: 25.19
UniProt: O60890 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60890 NP_002538.1 802 91641 S626 P N G T I T S S I E P P K P P
Chimpanzee Pan troglodytes Q7YQL6 802 91596 S626 P N G T I T S S I E P P K P P
Rhesus Macaque Macaca mulatta XP_001100242 802 91570 S626 P N G T I T G S I E T P K P P
Dog Lupus familis XP_849086 725 83009 Q566 S E D D I Q H Q T P N G I I T
Cat Felis silvestris
Mouse Mus musculus Q99J31 802 91966 N626 P N G T I T S N L D P P K L L
Rat Rattus norvegicus P0CAX5 802 91820 N626 P N G T I A S N L D P P K Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510470 781 87924 S599 A G I P W I A S S P P S N G Q
Chicken Gallus gallus Q5ZMW5 760 86506 L601 P S C S E R P L T L F H T A Q
Frog Xenopus laevis Q5U4T3 771 87657 E613 T S H S S E K E E K R N S V N
Zebra Danio Brachydanio rerio Q6ZM89 805 91116 S634 T F S S S P S S T P M G S M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.6 86.4 N.A. 91.7 91.5 N.A. 46.3 45.8 45.6 50 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.6 87.6 N.A. 95.6 95 N.A. 61 63.3 62.2 65.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 66.6 60 N.A. 13.3 6.6 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 6.6 N.A. 86.6 80 N.A. 20 20 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 10 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 0 20 0 0 0 0 0 % D
% Glu: 0 10 0 0 10 10 0 10 10 30 0 0 0 0 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 50 0 0 0 10 0 0 0 0 20 0 10 0 % G
% His: 0 0 10 0 0 0 10 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 60 10 0 0 30 0 0 0 10 10 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 10 0 0 50 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 20 10 0 0 0 10 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % M
% Asn: 0 50 0 0 0 0 0 20 0 0 10 10 10 0 10 % N
% Pro: 60 0 0 10 0 10 10 0 0 30 50 50 0 30 30 % P
% Gln: 0 0 0 0 0 10 0 10 0 0 0 0 0 10 20 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 20 10 30 20 0 50 50 10 0 0 10 20 0 0 % S
% Thr: 20 0 0 50 0 40 0 0 30 0 10 0 10 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _