KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPHN1
All Species:
18.79
Human Site:
T689
Identified Species:
45.93
UniProt:
O60890
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60890
NP_002538.1
802
91641
T689
T
K
I
T
P
K
A
T
N
G
P
M
P
G
S
Chimpanzee
Pan troglodytes
Q7YQL6
802
91596
T689
T
K
I
T
P
K
A
T
N
G
P
M
P
G
S
Rhesus Macaque
Macaca mulatta
XP_001100242
802
91570
T689
T
K
I
T
P
K
A
T
N
G
P
M
P
G
S
Dog
Lupus familis
XP_849086
725
83009
K622
C
P
E
V
D
V
G
K
L
V
S
R
L
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99J31
802
91966
S689
T
K
A
T
P
K
A
S
N
G
P
V
P
G
S
Rat
Rattus norvegicus
P0CAX5
802
91820
S689
T
K
A
I
P
K
A
S
N
G
P
V
P
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510470
781
87924
G655
P
I
D
L
V
K
K
G
P
Y
G
L
S
G
L
Chicken
Gallus gallus
Q5ZMW5
760
86506
K657
D
L
E
L
E
V
I
K
P
N
R
P
N
S
L
Frog
Xenopus laevis
Q5U4T3
771
87657
N668
S
R
P
N
S
L
L
N
P
K
N
I
S
G
L
Zebra Danio
Brachydanio rerio
Q6ZM89
805
91116
S694
C
T
T
S
P
D
S
S
S
K
E
D
A
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
86.4
N.A.
91.7
91.5
N.A.
46.3
45.8
45.6
50
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
87.6
N.A.
95.6
95
N.A.
61
63.3
62.2
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
80
73.3
N.A.
13.3
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
93.3
86.6
N.A.
20
0
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
50
0
0
0
0
0
10
0
0
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
10
0
0
0
0
0
10
0
0
10
% D
% Glu:
0
0
20
0
10
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
0
50
10
0
0
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
30
10
0
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
50
0
0
0
60
10
20
0
20
0
0
0
0
10
% K
% Leu:
0
10
0
20
0
10
10
0
10
0
0
10
10
0
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
50
10
10
0
10
10
0
% N
% Pro:
10
10
10
0
60
0
0
0
30
0
50
10
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
10
0
0
10
10
0
10
30
10
0
10
0
20
10
50
% S
% Thr:
50
10
10
40
0
0
0
30
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
20
0
0
0
10
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _