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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOX2
All Species:
21.21
Human Site:
S255
Identified Species:
51.85
UniProt:
O60902
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60902
NP_001157150.1
331
34953
S255
Q
A
Q
L
Q
L
D
S
A
V
A
H
A
H
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102324
355
37643
S279
Q
A
Q
L
Q
L
D
S
A
V
A
H
A
H
H
Dog
Lupus familis
XP_542854
302
33528
S226
Q
A
Q
L
Q
L
D
S
A
V
A
H
A
H
H
Cat
Felis silvestris
Mouse
Mus musculus
P70390
331
34887
S255
Q
A
Q
L
Q
L
D
S
A
V
A
H
A
H
H
Rat
Rattus norvegicus
O35750
237
26202
L174
H
H
H
L
H
P
H
L
A
A
H
G
P
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507913
401
45133
S325
Q
A
Q
L
Q
L
D
S
A
V
A
H
A
H
H
Chicken
Gallus gallus
Q9PVX0
317
34038
S232
P
G
G
A
A
L
Q
S
L
P
G
F
A
A
P
Frog
Xenopus laevis
O42201
322
36065
S240
S
N
S
T
A
L
Q
S
L
P
G
F
V
T
T
Zebra Danio
Brachydanio rerio
O42357
327
37134
S235
P
L
D
P
W
L
S
S
P
L
S
S
A
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120111
373
39859
G286
R
L
H
P
P
I
Q
G
A
G
G
N
I
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.2
84.2
N.A.
98.4
70
N.A.
64.3
29.6
26.5
22.9
N.A.
N.A.
36.7
N.A.
N.A.
Protein Similarity:
100
N.A.
93.2
85.5
N.A.
98.7
70.3
N.A.
67.5
39.8
38.3
38.3
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
20
13.3
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
100
20
13.3
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
10
20
0
0
0
70
10
50
0
70
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
50
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
10
0
10
30
10
0
0
0
% G
% His:
10
10
20
0
10
0
10
0
0
0
10
50
0
50
50
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
60
0
80
0
10
20
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
20
0
0
20
10
10
0
0
10
20
0
0
10
0
20
% P
% Gln:
50
0
50
0
50
0
30
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
0
0
10
80
0
0
10
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
30
20
% T
% Val:
0
0
0
0
0
0
0
0
0
50
0
0
10
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _