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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOX2
All Species:
20
Human Site:
Y25
Identified Species:
48.89
UniProt:
O60902
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60902
NP_001157150.1
331
34953
Y25
E
K
K
E
A
I
T
Y
R
E
V
L
E
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102324
355
37643
Y25
E
K
K
E
A
I
T
Y
R
E
V
L
E
S
G
Dog
Lupus familis
XP_542854
302
33528
Y25
E
K
K
E
A
I
T
Y
R
E
V
L
E
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P70390
331
34887
Y25
E
K
K
E
A
I
T
Y
R
E
V
L
E
S
G
Rat
Rattus norvegicus
O35750
237
26202
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507913
401
45133
Y25
E
K
K
E
V
I
T
Y
R
E
V
L
E
S
G
Chicken
Gallus gallus
Q9PVX0
317
34038
P29
A
R
S
P
G
G
N
P
S
R
L
H
S
I
E
Frog
Xenopus laevis
O42201
322
36065
S33
G
N
P
S
R
L
H
S
I
E
A
I
L
G
F
Zebra Danio
Brachydanio rerio
O42357
327
37134
G34
G
G
V
S
G
I
S
G
R
V
H
S
I
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120111
373
39859
T25
E
H
A
A
C
R
T
T
T
E
R
P
P
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.2
84.2
N.A.
98.4
70
N.A.
64.3
29.6
26.5
22.9
N.A.
N.A.
36.7
N.A.
N.A.
Protein Similarity:
100
N.A.
93.2
85.5
N.A.
98.7
70.3
N.A.
67.5
39.8
38.3
38.3
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
93.3
0
6.6
13.3
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
0
N.A.
93.3
13.3
20
20
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
40
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
60
0
0
50
0
0
0
0
0
70
0
0
50
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
20
10
0
0
20
10
0
10
0
0
0
0
0
10
50
% G
% His:
0
10
0
0
0
0
10
0
0
0
10
10
0
0
0
% H
% Ile:
0
0
0
0
0
60
0
0
10
0
0
10
10
10
0
% I
% Lys:
0
50
50
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
10
50
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
10
0
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
10
0
0
60
10
10
0
0
0
0
% R
% Ser:
0
0
10
20
0
0
10
10
10
0
0
10
10
60
0
% S
% Thr:
0
0
0
0
0
0
60
10
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
10
0
0
0
0
10
50
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _