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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL1X
All Species:
7.27
Human Site:
S223
Identified Species:
12.31
UniProt:
O60907
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60907
NP_001132938.1
577
62496
S223
G
E
V
E
I
P
S
S
K
A
T
V
L
R
G
Chimpanzee
Pan troglodytes
XP_001140707
575
62427
T221
L
K
I
E
L
T
M
T
K
A
T
C
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001089901
518
56436
C179
H
E
S
E
V
F
I
C
A
W
N
P
V
S
D
Dog
Lupus familis
XP_853719
630
67867
N276
G
D
V
E
I
P
P
N
K
A
T
V
L
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE7
527
56784
I187
G
H
E
S
E
V
F
I
C
A
W
N
P
V
S
Rat
Rattus norvegicus
NP_001102411
514
55652
C175
H
E
S
E
V
F
I
C
A
W
N
P
V
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516513
527
56747
I187
G
H
E
S
E
V
F
I
C
A
W
N
P
V
S
Chicken
Gallus gallus
NP_001153226
523
56567
I183
G
H
E
S
E
V
F
I
C
A
W
N
P
V
S
Frog
Xenopus laevis
Q6GPC6
522
56266
C183
H
E
S
E
V
F
I
C
A
W
N
P
V
S
D
Zebra Danio
Brachydanio rerio
NP_001076463
510
55488
V171
L
R
G
H
E
S
E
V
F
I
C
A
W
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RJ9
700
72369
S346
E
N
I
E
I
P
E
S
K
A
R
V
L
R
G
Honey Bee
Apis mellifera
XP_393667
512
56104
C173
H
E
S
E
V
F
I
C
A
W
N
P
T
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198347
493
53832
S154
T
V
L
R
G
H
E
S
E
V
F
S
C
A
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
R134
G
S
G
D
T
T
V
R
L
W
D
L
Y
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
88.9
83
N.A.
86.3
78.8
N.A.
86.1
86.1
80
75.5
N.A.
50.5
66
N.A.
69.3
Protein Similarity:
100
95.6
89.2
86.5
N.A.
88.7
84.2
N.A.
88.5
88.5
85.4
82.8
N.A.
60.5
74.1
N.A.
75.7
P-Site Identity:
100
40
13.3
80
N.A.
13.3
13.3
N.A.
13.3
13.3
13.3
0
N.A.
66.6
13.3
N.A.
6.6
P-Site Similarity:
100
66.6
26.6
93.3
N.A.
13.3
26.6
N.A.
13.3
13.3
26.6
0
N.A.
73.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
29
50
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
29
22
0
8
8
8
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
8
0
0
0
29
% D
% Glu:
8
36
22
58
29
0
22
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
29
22
0
8
0
8
0
0
0
0
% F
% Gly:
43
0
15
0
8
0
0
0
0
0
0
0
0
0
22
% G
% His:
29
22
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
22
0
29
22
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
29
0
0
0
0
0
0
% K
% Leu:
15
0
8
0
8
0
0
0
8
0
0
8
29
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
29
22
0
8
0
% N
% Pro:
0
0
0
0
0
22
8
0
0
0
0
29
22
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
8
0
0
29
0
% R
% Ser:
0
8
29
22
0
8
8
22
0
0
0
8
0
22
22
% S
% Thr:
8
0
0
0
8
15
0
8
0
0
22
0
8
15
0
% T
% Val:
0
8
15
0
29
22
8
8
0
8
0
22
22
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
36
22
0
8
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _