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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL1X All Species: 17.27
Human Site: S251 Identified Species: 29.23
UniProt: O60907 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60907 NP_001132938.1 577 62496 S251 S D L L A S G S G D S T A R I
Chimpanzee Pan troglodytes XP_001140707 575 62427 A249 Q K I T V T Q A G X S T A R I
Rhesus Macaque Macaca mulatta XP_001089901 518 56436 N207 W N L N E N S N G G S T Q L V
Dog Lupus familis XP_853719 630 67867 S304 S D L L A S G S G D S T A R I
Cat Felis silvestris
Mouse Mus musculus Q9QXE7 527 56784 S215 I W N L N E N S N G G S T Q L
Rat Rattus norvegicus NP_001102411 514 55652 T203 W N L S E N S T S G P T Q L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516513 527 56747 S215 I W N L N E N S N G G S T Q L
Chicken Gallus gallus NP_001153226 523 56567 S211 I W N L N E N S N S G S T Q L
Frog Xenopus laevis Q6GPC6 522 56266 T211 W N L S E N S T S G S T Q L V
Zebra Danio Brachydanio rerio NP_001076463 510 55488 E199 A R I W N L I E N S S T Q L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RJ9 700 72369 S374 R D L L A S G S G D S T A R I
Honey Bee Apis mellifera XP_393667 512 56104 Q201 W D M S G S S Q A P N Q L V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198347 493 53832 L182 S T A R I W N L S E G Q N S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879 D162 L T V A W S P D G K H L V S G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 88.9 83 N.A. 86.3 78.8 N.A. 86.1 86.1 80 75.5 N.A. 50.5 66 N.A. 69.3
Protein Similarity: 100 95.6 89.2 86.5 N.A. 88.7 84.2 N.A. 88.5 88.5 85.4 82.8 N.A. 60.5 74.1 N.A. 75.7
P-Site Identity: 100 40 26.6 100 N.A. 13.3 13.3 N.A. 13.3 13.3 20 13.3 N.A. 93.3 13.3 N.A. 6.6
P-Site Similarity: 100 60 53.3 100 N.A. 33.3 40 N.A. 33.3 33.3 46.6 33.3 N.A. 93.3 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 22 0 0 8 8 0 0 0 29 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 29 0 0 0 0 0 8 0 22 0 0 0 0 0 % D
% Glu: 0 0 0 0 22 22 0 8 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 22 0 43 36 29 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 22 0 15 0 8 0 8 0 0 0 0 0 0 0 29 % I
% Lys: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 8 0 43 43 0 8 0 8 0 0 0 8 8 29 29 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 22 22 8 29 22 29 8 29 0 8 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 8 0 0 0 15 29 22 0 % Q
% Arg: 8 8 0 8 0 0 0 0 0 0 0 0 0 29 0 % R
% Ser: 22 0 0 22 0 36 29 43 22 15 50 22 0 15 8 % S
% Thr: 0 15 0 8 0 8 0 15 0 0 0 58 22 0 0 % T
% Val: 0 0 8 0 8 0 0 0 0 0 0 0 8 8 29 % V
% Trp: 29 22 0 8 8 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _