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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL1X All Species: 13.64
Human Site: T486 Identified Species: 23.08
UniProt: O60907 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60907 NP_001132938.1 577 62496 T486 A S A S F D S T V R L W D I E
Chimpanzee Pan troglodytes XP_001140707 575 62427 T484 A S A S F D S T V R L W D I E
Rhesus Macaque Macaca mulatta XP_001089901 518 56436 W431 F D S T V R L W D I E R G V C
Dog Lupus familis XP_853719 630 67867 T539 A S A S F D S T V R L W D V E
Cat Felis silvestris
Mouse Mus musculus Q9QXE7 527 56784 L439 S F D S T V R L W D V E R G V
Rat Rattus norvegicus NP_001102411 514 55652 W427 F D S T V R L W D V D R G I C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516513 527 56747 L439 S F D S T V R L W D V E R G V
Chicken Gallus gallus NP_001153226 523 56567 L435 S F D S T V R L W D V D R G V
Frog Xenopus laevis Q6GPC6 522 56266 W435 F D S T V R L W D V D R G I C
Zebra Danio Brachydanio rerio NP_001076463 510 55488 W423 F D S T V R L W D V D R G V C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RJ9 700 72369 T608 A S A S F D S T V R L W D V E
Honey Bee Apis mellifera XP_393667 512 56104 D425 D S T V R L W D V E R G A C I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198347 493 53832 W406 F D S T V R L W D V E R G I C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879 L386 S F D K S V R L W N G I T G Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 88.9 83 N.A. 86.3 78.8 N.A. 86.1 86.1 80 75.5 N.A. 50.5 66 N.A. 69.3
Protein Similarity: 100 95.6 89.2 86.5 N.A. 88.7 84.2 N.A. 88.5 88.5 85.4 82.8 N.A. 60.5 74.1 N.A. 75.7
P-Site Identity: 100 100 0 93.3 N.A. 6.6 6.6 N.A. 6.6 6.6 6.6 0 N.A. 93.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 20 100 N.A. 20 20 N.A. 20 20 20 20 N.A. 100 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 29 0 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 36 % C
% Asp: 8 36 29 0 0 29 0 8 36 22 22 8 29 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 15 15 0 0 29 % E
% Phe: 36 29 0 0 29 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 8 36 29 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 8 0 36 8 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 36 29 0 0 29 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 8 36 29 0 0 29 8 36 22 0 0 % R
% Ser: 29 36 36 50 8 0 29 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 36 22 0 0 29 0 0 0 0 8 0 0 % T
% Val: 0 0 0 8 36 29 0 0 36 29 22 0 0 29 22 % V
% Trp: 0 0 0 0 0 0 8 36 29 0 0 29 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _