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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL1X
All Species:
16.06
Human Site:
Y543
Identified Species:
27.18
UniProt:
O60907
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60907
NP_001132938.1
577
62496
Y543
S
G
N
L
V
H
S
Y
R
G
T
G
G
I
F
Chimpanzee
Pan troglodytes
XP_001140707
575
62427
Y541
S
G
N
L
V
H
S
Y
R
G
T
G
G
I
F
Rhesus Macaque
Macaca mulatta
XP_001089901
518
56436
G488
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
W
Dog
Lupus familis
XP_853719
630
67867
Y596
S
G
S
L
V
H
S
Y
R
G
T
G
G
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE7
527
56784
T496
L
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
Rat
Rattus norvegicus
NP_001102411
514
55652
G484
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516513
527
56747
T496
L
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
Chicken
Gallus gallus
NP_001153226
523
56567
T492
L
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
Frog
Xenopus laevis
Q6GPC6
522
56266
G492
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
W
Zebra Danio
Brachydanio rerio
NP_001076463
510
55488
G480
V
N
S
Y
R
G
T
G
G
I
F
E
V
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RJ9
700
72369
Y665
T
G
Q
L
V
H
S
Y
K
G
T
G
G
I
F
Honey Bee
Apis mellifera
XP_393667
512
56104
G482
H
S
Y
Q
G
T
G
G
I
F
E
V
C
W
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198347
493
53832
G463
V
H
S
Y
R
G
T
G
G
I
F
E
V
C
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
H443
L
K
Q
D
L
P
G
H
A
D
E
V
F
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
88.9
83
N.A.
86.3
78.8
N.A.
86.1
86.1
80
75.5
N.A.
50.5
66
N.A.
69.3
Protein Similarity:
100
95.6
89.2
86.5
N.A.
88.7
84.2
N.A.
88.5
88.5
85.4
82.8
N.A.
60.5
74.1
N.A.
75.7
P-Site Identity:
100
100
0
93.3
N.A.
6.6
0
N.A.
6.6
6.6
0
0
N.A.
80
0
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
20
20
N.A.
20
20
20
20
N.A.
93.3
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
36
22
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
15
36
22
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
36
22
8
0
29
% F
% Gly:
0
29
0
0
8
36
36
43
58
50
0
29
29
0
0
% G
% His:
8
29
22
0
0
29
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
36
22
0
0
29
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
29
0
0
29
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
15
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
36
22
0
0
22
0
0
0
0
0
0
% R
% Ser:
22
8
43
22
0
0
29
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
36
22
0
0
29
0
0
0
0
% T
% Val:
36
22
0
0
29
0
0
0
0
0
0
15
36
22
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
36
% W
% Tyr:
0
0
8
36
22
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _