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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUS1
All Species:
25.15
Human Site:
T130
Identified Species:
55.33
UniProt:
O60921
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60921
NP_004498.1
280
31691
T130
S
S
S
S
R
I
V
T
H
D
I
P
I
K
V
Chimpanzee
Pan troglodytes
XP_001152134
259
29268
P118
D
I
P
I
K
V
I
P
R
K
L
W
K
D
L
Rhesus Macaque
Macaca mulatta
XP_001088000
280
31699
T130
S
S
S
S
R
I
V
T
H
D
I
P
I
K
V
Dog
Lupus familis
XP_848291
407
45077
T257
S
S
S
S
R
V
V
T
H
D
I
P
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQY8
280
31661
V130
S
S
S
S
R
I
V
V
H
D
I
P
I
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507001
139
15756
D29
I
V
L
I
P
H
K
D
P
N
C
W
F
R
Q
Chicken
Gallus gallus
XP_426029
271
30461
T130
S
S
S
S
R
I
V
T
H
D
I
P
V
R
V
Frog
Xenopus laevis
NP_001082564
282
32021
T130
S
S
S
S
R
I
V
T
H
D
I
P
V
S
V
Zebra Danio
Brachydanio rerio
NP_001082965
284
32061
T130
S
S
L
S
R
V
V
T
H
D
L
P
V
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477426
278
30493
R131
T
S
S
S
T
E
A
R
E
V
V
H
D
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786829
280
32047
T128
T
G
H
S
R
T
I
T
H
D
I
P
V
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
99.2
57.2
N.A.
86
N.A.
N.A.
33.2
71
71.2
64.4
N.A.
31.7
N.A.
N.A.
47.5
Protein Similarity:
100
92.5
100
64.6
N.A.
92.5
N.A.
N.A.
40.7
84.2
85.8
81.3
N.A.
52.8
N.A.
N.A.
72.1
P-Site Identity:
100
0
100
86.6
N.A.
93.3
N.A.
N.A.
0
86.6
86.6
66.6
N.A.
20
N.A.
N.A.
53.3
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
N.A.
N.A.
13.3
100
93.3
86.6
N.A.
33.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
73
0
0
10
19
0
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
10
0
0
73
0
0
10
0
0
0
% H
% Ile:
10
10
0
19
0
46
19
0
0
0
64
0
28
10
0
% I
% Lys:
0
0
0
0
10
0
10
0
0
10
0
0
10
37
0
% K
% Leu:
0
0
19
0
0
0
0
0
0
0
19
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
0
0
10
10
0
0
73
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
73
0
0
10
10
0
0
0
0
19
0
% R
% Ser:
64
73
64
82
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
19
0
0
0
10
10
0
64
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
28
64
10
0
10
10
0
46
10
73
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _