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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUS1
All Species:
26.67
Human Site:
Y159
Identified Species:
58.67
UniProt:
O60921
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60921
NP_004498.1
280
31691
Y159
P
D
P
D
V
S
I
Y
L
P
V
L
K
T
M
Chimpanzee
Pan troglodytes
XP_001152134
259
29268
Y138
P
D
P
D
V
S
I
Y
L
P
V
L
K
T
M
Rhesus Macaque
Macaca mulatta
XP_001088000
280
31699
Y159
P
D
P
D
V
S
I
Y
L
P
V
L
K
T
M
Dog
Lupus familis
XP_848291
407
45077
Y286
P
D
S
D
V
S
I
Y
L
P
A
L
K
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQY8
280
31661
C159
P
D
C
D
V
S
I
C
L
P
A
L
K
M
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507001
139
15756
S46
Q
V
I
E
A
N
L
S
G
E
M
N
L
K
I
Chicken
Gallus gallus
XP_426029
271
30461
Y159
P
D
F
D
V
S
I
Y
L
P
V
L
K
T
M
Frog
Xenopus laevis
NP_001082564
282
32021
Y159
P
E
F
D
V
S
I
Y
L
P
A
L
K
T
M
Zebra Danio
Brachydanio rerio
NP_001082965
284
32061
Y159
P
E
F
D
V
S
I
Y
L
P
P
L
K
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477426
278
30493
G163
P
N
S
Q
L
A
L
G
L
P
S
L
R
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786829
280
32047
C157
P
D
F
D
A
T
I
C
M
P
P
L
K
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
99.2
57.2
N.A.
86
N.A.
N.A.
33.2
71
71.2
64.4
N.A.
31.7
N.A.
N.A.
47.5
Protein Similarity:
100
92.5
100
64.6
N.A.
92.5
N.A.
N.A.
40.7
84.2
85.8
81.3
N.A.
52.8
N.A.
N.A.
72.1
P-Site Identity:
100
100
100
86.6
N.A.
73.3
N.A.
N.A.
0
93.3
80
80
N.A.
26.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
N.A.
N.A.
33.3
93.3
86.6
86.6
N.A.
66.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
10
0
0
0
0
28
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
19
0
0
0
0
0
0
0
% C
% Asp:
0
64
0
82
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
10
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
82
0
0
0
0
0
0
0
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
82
10
0
% K
% Leu:
0
0
0
0
10
0
19
0
82
0
0
91
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
73
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
91
0
28
0
0
0
0
0
0
91
19
0
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
19
0
0
73
0
10
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
64
0
% T
% Val:
0
10
0
0
73
0
0
0
0
0
37
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _