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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HUS1 All Species: 21.52
Human Site: Y80 Identified Species: 47.33
UniProt: O60921 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60921 NP_004498.1 280 31691 Y80 S A E N N E I Y L E L T S E N
Chimpanzee Pan troglodytes XP_001152134 259 29268 S68 E L T S E N L S R A L K T A Q
Rhesus Macaque Macaca mulatta XP_001088000 280 31699 Y80 S A E N N E I Y L E L T S E N
Dog Lupus familis XP_848291 407 45077 Y207 S A E N N A I Y L D L T A E N
Cat Felis silvestris
Mouse Mus musculus Q8BQY8 280 31661 Y80 S E E N N E I Y L E L T S E N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507001 139 15756
Chicken Gallus gallus XP_426029 271 30461 Y80 A A D H N E I Y L E L M P E N
Frog Xenopus laevis NP_001082564 282 32021 F80 C V E H N E I F L E L I P E N
Zebra Danio Brachydanio rerio NP_001082965 284 32061 F80 S A D A N E I F L E V A P E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477426 278 30493 V81 H P D Q E Y I V L G V S S A N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786829 280 32047 Y78 A E D A N E I Y M E V N P D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 99.2 57.2 N.A. 86 N.A. N.A. 33.2 71 71.2 64.4 N.A. 31.7 N.A. N.A. 47.5
Protein Similarity: 100 92.5 100 64.6 N.A. 92.5 N.A. N.A. 40.7 84.2 85.8 81.3 N.A. 52.8 N.A. N.A. 72.1
P-Site Identity: 100 6.6 100 80 N.A. 93.3 N.A. N.A. 0 66.6 60 60 N.A. 26.6 N.A. N.A. 33.3
P-Site Similarity: 100 26.6 100 93.3 N.A. 93.3 N.A. N.A. 0 86.6 73.3 80 N.A. 46.6 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 46 0 19 0 10 0 0 0 10 0 10 10 19 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 37 0 0 0 0 0 0 10 0 0 0 10 10 % D
% Glu: 10 19 46 0 19 64 0 0 0 64 0 0 0 64 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 10 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 82 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 0 0 10 0 73 0 64 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % M
% Asn: 0 0 0 37 73 10 0 0 0 0 0 10 0 0 73 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 37 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 46 0 0 10 0 0 0 10 0 0 0 10 37 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 37 10 0 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 28 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 55 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _