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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PFDN1 All Species: 34.24
Human Site: Y100 Identified Species: 62.78
UniProt: O60925 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60925 NP_002613.2 122 14210 Y100 E L E Q K K S Y L E R S V K E
Chimpanzee Pan troglodytes XP_001137036 117 13529 F100 E L E Q K K P F L S W G M G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848520 122 14220 Y100 E L E Q K K S Y L E R S V K E
Cat Felis silvestris
Mouse Mus musculus Q9CWM4 122 14236 Y100 E L E Q K K S Y L E R S V K E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505536 209 22997 A167 I R P E K P S A L L A A L M A
Chicken Gallus gallus XP_414472 122 14191 Y100 E L E Q K K S Y L E R S V K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5D016 122 13969 Y100 E L E Q K K T Y L E R S V K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608992 126 14731 F99 L L E K K K E F L Q K S L K S
Honey Bee Apis mellifera XP_001122412 126 14881 Y100 N L E N N K T Y L Q Q N L K E
Nematode Worm Caenorhab. elegans Q17827 117 13878 Y97 A I E K Q K D Y L E K G L V E
Sea Urchin Strong. purpuratus XP_781962 122 13911 Y98 K V Q S N K T Y L E R T L K D
Poplar Tree Populus trichocarpa XP_002308134 129 14925 Y97 S L Q T S K E Y L E K H M S E
Maize Zea mays NP_001148596 129 14871 Y97 S M Q T S K D Y L E K Q Q G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.9 N.A. 99.1 N.A. 96.7 N.A. N.A. 49.2 91.8 N.A. 77.8 N.A. 35.7 47.6 33.6 47.5
Protein Similarity: 100 85.2 N.A. 99.1 N.A. 98.3 N.A. N.A. 54 96.7 N.A. 89.3 N.A. 63.4 69.8 59.8 74.5
P-Site Identity: 100 46.6 N.A. 100 N.A. 100 N.A. N.A. 20 100 N.A. 86.6 N.A. 46.6 46.6 40 40
P-Site Similarity: 100 60 N.A. 100 N.A. 100 N.A. N.A. 40 100 N.A. 100 N.A. 80 80 73.3 86.6
Percent
Protein Identity: 35.6 37.2 N.A. N.A. N.A. N.A.
Protein Similarity: 55 56.5 N.A. N.A. N.A. N.A.
P-Site Identity: 40 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 60 53.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 8 0 0 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 16 % D
% Glu: 47 0 70 8 0 0 16 0 0 70 0 0 0 0 62 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 16 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 16 62 93 0 0 0 0 31 0 0 62 0 % K
% Leu: 8 70 0 0 0 0 0 0 100 8 0 0 39 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 16 8 0 % M
% Asn: 8 0 0 8 16 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 8 0 0 8 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 24 47 8 0 0 0 0 16 8 8 8 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 47 0 0 0 0 % R
% Ser: 16 0 0 8 16 0 39 0 0 8 0 47 0 8 8 % S
% Thr: 0 0 0 16 0 0 24 0 0 0 0 8 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 39 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _