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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH1
All Species:
11.21
Human Site:
S74
Identified Species:
20.56
UniProt:
O60930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60930
NP_002927.2
286
32064
S74
A
W
A
F
V
R
K
S
A
S
P
E
V
S
E
Chimpanzee
Pan troglodytes
XP_001150506
286
32080
S74
A
W
A
F
V
R
K
S
A
S
P
E
V
S
E
Rhesus Macaque
Macaca mulatta
XP_001097079
286
32042
S74
A
W
T
F
V
R
K
S
A
S
P
E
V
S
E
Dog
Lupus familis
XP_532858
285
31856
R73
E
E
A
W
A
F
V
R
K
P
A
G
L
D
G
Cat
Felis silvestris
Mouse
Mus musculus
O70338
285
31786
S73
E
A
W
A
F
V
R
S
S
S
S
P
D
G
S
Rat
Rattus norvegicus
Q5BK46
285
31755
S73
E
A
W
A
F
V
R
S
S
S
S
P
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990329
293
32481
H81
Q
S
A
P
A
E
T
H
G
A
S
A
V
A
Q
Frog
Xenopus laevis
NP_001084684
300
33514
V86
S
L
K
G
S
T
S
V
E
T
K
E
P
P
T
Zebra Danio
Brachydanio rerio
NP_001002659
276
30360
N64
A
S
S
S
A
G
A
N
G
C
E
L
E
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995777
314
35173
K97
I
E
V
N
K
N
P
K
Y
T
D
E
W
P
E
Honey Bee
Apis mellifera
XP_395566
261
29754
L63
K
K
E
N
N
E
N
L
S
S
L
L
G
K
R
Nematode Worm
Caenorhab. elegans
NP_001040786
251
27998
N53
A
R
K
F
V
A
D
N
M
S
V
P
G
S
K
Sea Urchin
Strong. purpuratus
XP_789772
234
26071
K36
G
F
P
G
A
K
F
K
K
F
G
T
E
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.7
82.1
N.A.
78.3
77.2
N.A.
N.A.
59.3
55
50.3
N.A.
33.7
36
37
44
Protein Similarity:
100
99.6
96.5
87
N.A.
87
85.3
N.A.
N.A.
72
66.3
63.2
N.A.
46.5
51.4
53.1
55.2
P-Site Identity:
100
100
93.3
6.6
N.A.
13.3
13.3
N.A.
N.A.
13.3
6.6
6.6
N.A.
13.3
6.6
33.3
6.6
P-Site Similarity:
100
100
93.3
20
N.A.
26.6
26.6
N.A.
N.A.
33.3
20
20
N.A.
20
13.3
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
16
31
16
31
8
8
0
24
8
8
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
0
16
8
0
% D
% Glu:
24
16
8
0
0
16
0
0
8
0
8
39
16
0
39
% E
% Phe:
0
8
0
31
16
8
8
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
16
0
8
0
0
16
0
8
8
16
16
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
16
0
8
8
24
16
16
0
8
0
0
8
8
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
8
16
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
8
8
8
16
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
8
0
0
8
24
24
8
16
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
8
0
0
0
24
16
8
0
0
0
0
0
0
8
% R
% Ser:
8
16
8
8
8
0
8
39
24
54
24
0
0
31
16
% S
% Thr:
0
0
8
0
0
8
8
0
0
16
0
8
0
0
8
% T
% Val:
0
0
8
0
31
16
8
8
0
0
8
0
31
8
0
% V
% Trp:
0
24
16
8
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _