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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH1
All Species:
12.42
Human Site:
S96
Identified Species:
22.78
UniProt:
O60930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60930
NP_002927.2
286
32064
S96
Q
E
S
E
A
K
A
S
K
R
L
R
E
P
L
Chimpanzee
Pan troglodytes
XP_001150506
286
32080
S96
Q
E
S
E
A
K
A
S
K
R
L
R
E
P
L
Rhesus Macaque
Macaca mulatta
XP_001097079
286
32042
S96
Q
E
L
Q
M
K
A
S
K
R
L
R
E
P
L
Dog
Lupus familis
XP_532858
285
31856
K95
H
E
K
E
S
Q
V
K
A
S
K
R
L
R
E
Cat
Felis silvestris
Mouse
Mus musculus
O70338
285
31786
T95
E
Q
K
S
Q
A
K
T
S
K
R
P
R
E
P
Rat
Rattus norvegicus
Q5BK46
285
31755
T95
V
Q
K
L
Q
V
K
T
S
K
R
P
R
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990329
293
32481
C103
E
P
E
T
D
V
L
C
C
N
A
C
K
R
P
Frog
Xenopus laevis
NP_001084684
300
33514
S108
L
H
N
V
I
P
Q
S
R
R
K
R
P
L
L
Zebra Danio
Brachydanio rerio
NP_001002659
276
30360
G86
S
S
M
A
V
S
F
G
S
K
R
T
H
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995777
314
35173
N119
D
D
L
P
D
I
L
N
R
K
R
K
G
T
T
Honey Bee
Apis mellifera
XP_395566
261
29754
K85
D
N
K
K
S
L
K
K
Q
K
Q
M
N
L
E
Nematode Worm
Caenorhab. elegans
NP_001040786
251
27998
R75
T
S
S
A
T
R
K
R
T
H
E
G
T
K
F
Sea Urchin
Strong. purpuratus
XP_789772
234
26071
P58
T
N
D
C
S
S
A
P
K
S
C
S
S
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.7
82.1
N.A.
78.3
77.2
N.A.
N.A.
59.3
55
50.3
N.A.
33.7
36
37
44
Protein Similarity:
100
99.6
96.5
87
N.A.
87
85.3
N.A.
N.A.
72
66.3
63.2
N.A.
46.5
51.4
53.1
55.2
P-Site Identity:
100
100
80
20
N.A.
0
0
N.A.
N.A.
0
26.6
0
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
100
86.6
33.3
N.A.
26.6
20
N.A.
N.A.
13.3
40
6.6
N.A.
33.3
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
8
31
0
8
0
8
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
8
8
0
8
8
0
0
0
% C
% Asp:
16
8
8
0
16
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
16
31
8
24
0
0
0
0
0
0
8
0
24
16
24
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
31
8
0
24
31
16
31
39
16
8
8
8
0
% K
% Leu:
8
0
16
8
0
8
16
0
0
0
24
0
8
16
31
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
16
8
0
0
0
0
8
0
8
0
0
8
0
0
% N
% Pro:
0
8
0
8
0
8
0
8
0
0
0
16
8
24
31
% P
% Gln:
24
16
0
8
16
8
8
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
16
31
31
39
16
16
0
% R
% Ser:
8
16
24
8
24
16
0
31
24
16
0
8
8
0
0
% S
% Thr:
16
0
0
8
8
0
0
16
8
0
0
8
8
8
8
% T
% Val:
8
0
0
8
8
16
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _