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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH1
All Species:
16.06
Human Site:
T132
Identified Species:
29.44
UniProt:
O60930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60930
NP_002927.2
286
32064
T132
A
P
P
V
S
R
D
T
F
S
Y
M
G
D
F
Chimpanzee
Pan troglodytes
XP_001150506
286
32080
T132
A
P
P
V
S
R
D
T
F
S
Y
M
G
D
F
Rhesus Macaque
Macaca mulatta
XP_001097079
286
32042
T132
A
P
P
V
S
R
D
T
F
S
Y
M
G
D
F
Dog
Lupus familis
XP_532858
285
31856
M131
M
P
P
V
S
K
D
M
F
S
Y
M
G
E
F
Cat
Felis silvestris
Mouse
Mus musculus
O70338
285
31786
T131
A
A
V
V
S
K
D
T
F
S
Y
M
G
E
S
Rat
Rattus norvegicus
Q5BK46
285
31755
A131
A
A
L
V
S
K
D
A
F
S
Y
M
G
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990329
293
32481
K139
T
P
V
V
S
E
A
K
F
S
Y
M
G
E
F
Frog
Xenopus laevis
NP_001084684
300
33514
T144
L
P
S
S
H
N
G
T
F
T
Y
M
G
D
A
Zebra Danio
Brachydanio rerio
NP_001002659
276
30360
G122
T
G
T
T
S
S
D
G
F
T
Y
M
G
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995777
314
35173
F155
K
Q
V
G
A
F
Q
F
E
I
D
A
E
G
Y
Honey Bee
Apis mellifera
XP_395566
261
29754
T121
D
G
Y
V
N
V
Y
T
D
G
A
C
S
L
N
Nematode Worm
Caenorhab. elegans
NP_001040786
251
27998
C111
V
V
Y
T
D
G
A
C
S
S
N
G
T
K
N
Sea Urchin
Strong. purpuratus
XP_789772
234
26071
H94
Y
T
D
G
A
C
S
H
N
G
F
S
G
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.7
82.1
N.A.
78.3
77.2
N.A.
N.A.
59.3
55
50.3
N.A.
33.7
36
37
44
Protein Similarity:
100
99.6
96.5
87
N.A.
87
85.3
N.A.
N.A.
72
66.3
63.2
N.A.
46.5
51.4
53.1
55.2
P-Site Identity:
100
100
100
73.3
N.A.
66.6
60
N.A.
N.A.
60
46.6
46.6
N.A.
0
13.3
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
73.3
N.A.
N.A.
66.6
53.3
53.3
N.A.
13.3
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
16
0
0
16
0
16
8
0
0
8
8
0
8
16
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% C
% Asp:
8
0
8
0
8
0
54
0
8
0
8
0
0
39
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
0
0
8
31
0
% E
% Phe:
0
0
0
0
0
8
0
8
70
0
8
0
0
0
39
% F
% Gly:
0
16
0
16
0
8
8
8
0
16
0
8
77
8
0
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
24
0
8
0
0
0
0
0
8
8
% K
% Leu:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
70
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
8
0
8
0
0
0
16
% N
% Pro:
0
47
31
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
62
8
8
0
8
62
0
8
8
0
16
% S
% Thr:
16
8
8
16
0
0
0
47
0
16
0
0
8
0
0
% T
% Val:
8
8
24
62
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
0
0
0
8
0
0
0
70
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _