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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH1
All Species:
18.18
Human Site:
T37
Identified Species:
33.33
UniProt:
O60930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60930
NP_002927.2
286
32064
T37
A
V
R
R
G
R
K
T
G
V
F
L
T
W
N
Chimpanzee
Pan troglodytes
XP_001150506
286
32080
T37
A
V
R
R
G
R
K
T
G
V
F
L
T
W
N
Rhesus Macaque
Macaca mulatta
XP_001097079
286
32042
T37
A
V
R
R
G
R
K
T
G
V
F
L
T
W
N
Dog
Lupus familis
XP_532858
285
31856
A38
A
V
R
R
G
R
K
A
G
V
F
Q
T
W
S
Cat
Felis silvestris
Mouse
Mus musculus
O70338
285
31786
T37
A
V
R
R
G
R
R
T
G
V
F
L
S
W
S
Rat
Rattus norvegicus
Q5BK46
285
31755
T37
A
V
R
R
G
R
R
T
G
V
F
L
S
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990329
293
32481
R46
E
C
Q
Q
Q
V
N
R
F
P
S
A
S
F
K
Frog
Xenopus laevis
NP_001084684
300
33514
P38
A
V
R
T
G
R
K
P
G
V
Y
N
T
W
D
Zebra Danio
Brachydanio rerio
NP_001002659
276
30360
K32
E
C
K
H
Q
V
D
K
F
P
S
A
S
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995777
314
35173
G42
E
C
E
E
Q
V
K
G
F
K
N
A
K
Y
K
Honey Bee
Apis mellifera
XP_395566
261
29754
R32
E
Q
V
D
Q
F
P
R
P
I
F
R
K
F
H
Nematode Worm
Caenorhab. elegans
NP_001040786
251
27998
W22
Q
V
G
I
Y
R
T
W
N
E
C
K
T
Q
I
Sea Urchin
Strong. purpuratus
XP_789772
234
26071
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.7
82.1
N.A.
78.3
77.2
N.A.
N.A.
59.3
55
50.3
N.A.
33.7
36
37
44
Protein Similarity:
100
99.6
96.5
87
N.A.
87
85.3
N.A.
N.A.
72
66.3
63.2
N.A.
46.5
51.4
53.1
55.2
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
0
66.6
0
N.A.
6.6
6.6
20
0
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
26.6
80
20
N.A.
13.3
26.6
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
0
0
0
0
8
0
0
0
24
0
0
0
% A
% Cys:
0
24
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
31
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
24
0
54
0
0
24
0
% F
% Gly:
0
0
8
0
54
0
0
8
54
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
47
8
0
8
0
8
16
0
24
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
8
8
0
0
24
% N
% Pro:
0
0
0
0
0
0
8
8
8
16
0
0
0
0
0
% P
% Gln:
8
8
8
8
31
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
54
47
0
62
16
16
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
16
0
31
0
24
% S
% Thr:
0
0
0
8
0
0
8
39
0
0
0
0
47
0
0
% T
% Val:
0
62
8
0
0
24
0
0
0
54
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
54
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _