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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH1
All Species:
22.42
Human Site:
Y29
Identified Species:
41.11
UniProt:
O60930
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60930
NP_002927.2
286
32064
Y29
S
R
G
F
G
M
F
Y
A
V
R
R
G
R
K
Chimpanzee
Pan troglodytes
XP_001150506
286
32080
Y29
S
R
G
F
G
M
F
Y
A
V
R
R
G
R
K
Rhesus Macaque
Macaca mulatta
XP_001097079
286
32042
Y29
S
R
G
F
G
M
F
Y
A
V
R
R
G
R
K
Dog
Lupus familis
XP_532858
285
31856
Y30
C
S
S
L
S
M
F
Y
A
V
R
R
G
R
K
Cat
Felis silvestris
Mouse
Mus musculus
O70338
285
31786
Y29
I
C
G
L
G
M
F
Y
A
V
R
R
G
R
R
Rat
Rattus norvegicus
Q5BK46
285
31755
Y29
V
C
G
L
G
M
F
Y
A
V
R
R
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990329
293
32481
A38
T
G
V
Y
R
T
W
A
E
C
Q
Q
Q
V
N
Frog
Xenopus laevis
NP_001084684
300
33514
Y30
S
T
F
R
R
M
F
Y
A
V
R
T
G
R
K
Zebra Danio
Brachydanio rerio
NP_001002659
276
30360
E24
P
G
V
Y
Q
T
W
E
E
C
K
H
Q
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995777
314
35173
A34
S
G
V
Y
G
S
W
A
E
C
E
E
Q
V
K
Honey Bee
Apis mellifera
XP_395566
261
29754
K24
Y
N
T
W
L
E
C
K
E
Q
V
D
Q
F
P
Nematode Worm
Caenorhab. elegans
NP_001040786
251
27998
K14
Y
Y
A
V
A
R
G
K
Q
V
G
I
Y
R
T
Sea Urchin
Strong. purpuratus
XP_789772
234
26071
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.7
82.1
N.A.
78.3
77.2
N.A.
N.A.
59.3
55
50.3
N.A.
33.7
36
37
44
Protein Similarity:
100
99.6
96.5
87
N.A.
87
85.3
N.A.
N.A.
72
66.3
63.2
N.A.
46.5
51.4
53.1
55.2
P-Site Identity:
100
100
100
66.6
N.A.
73.3
73.3
N.A.
N.A.
0
66.6
0
N.A.
20
0
13.3
0
P-Site Similarity:
100
100
100
66.6
N.A.
80
80
N.A.
N.A.
33.3
66.6
20
N.A.
33.3
6.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
16
54
0
0
0
0
0
0
% A
% Cys:
8
16
0
0
0
0
8
0
0
24
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
0
0
8
0
8
31
0
8
8
0
0
0
% E
% Phe:
0
0
8
24
0
0
54
0
0
0
0
0
0
8
0
% F
% Gly:
0
24
39
0
47
0
8
0
0
0
8
0
54
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
16
0
0
8
0
0
0
47
% K
% Leu:
0
0
0
24
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
8
8
31
0
0
% Q
% Arg:
0
24
0
8
16
8
0
0
0
0
54
47
0
62
16
% R
% Ser:
39
8
8
0
8
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
8
8
0
0
16
0
0
0
0
0
8
0
0
8
% T
% Val:
8
0
24
8
0
0
0
0
0
62
8
0
0
24
0
% V
% Trp:
0
0
0
8
0
0
24
0
0
0
0
0
0
0
0
% W
% Tyr:
16
8
0
24
0
0
0
54
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _