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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNS
All Species:
38.18
Human Site:
S154
Identified Species:
70
UniProt:
O60931
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60931
NP_004928
367
41738
S154
I
M
N
W
R
R
K
S
V
I
G
L
S
F
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089732
367
41660
S154
I
M
N
W
R
R
K
S
V
I
G
L
S
F
D
Dog
Lupus familis
XP_548340
367
41826
S154
I
T
N
W
R
R
K
S
V
V
G
L
S
F
D
Cat
Felis silvestris
Mouse
Mus musculus
P57757
367
42185
S154
I
Q
N
W
R
R
K
S
V
I
G
L
S
F
D
Rat
Rattus norvegicus
XP_001080248
367
41895
S154
I
Q
N
W
R
R
K
S
V
V
G
L
S
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508868
605
66131
S392
Y
E
N
W
R
R
K
S
V
V
G
L
S
F
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084886
375
42407
S163
F
E
N
W
K
R
K
S
V
V
G
L
S
F
D
Zebra Danio
Brachydanio rerio
NP_001018407
384
43736
S159
Y
E
N
W
K
R
R
S
V
V
G
L
N
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCR7
397
44570
S159
W
S
N
Y
R
R
K
S
V
E
G
L
N
F
D
Honey Bee
Apis mellifera
XP_394902
297
34497
A87
L
V
G
F
I
M
Y
A
L
F
N
C
G
L
F
Nematode Worm
Caenorhab. elegans
Q09500
404
45376
S156
Y
L
N
F
K
R
K
S
V
V
G
L
N
F
D
Sea Urchin
Strong. purpuratus
XP_001199518
324
35859
N114
S
G
L
F
V
E
V
N
V
V
Q
S
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P17261
260
30098
Y50
L
N
T
A
G
Y
S
Y
L
V
I
S
I
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
84.7
N.A.
84.1
82
N.A.
46.1
N.A.
61.8
57.8
N.A.
39.7
42.2
34.1
42.7
Protein Similarity:
100
N.A.
98.9
91.8
N.A.
91.8
91.2
N.A.
53.3
N.A.
76
75.2
N.A.
57.9
58.5
50.2
58
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
86.6
N.A.
80
N.A.
73.3
60
N.A.
66.6
0
60
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
86.6
86.6
N.A.
80
33.3
93.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% D
% Glu:
0
24
0
0
0
8
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
24
0
0
0
0
0
8
0
0
0
85
8
% F
% Gly:
0
8
8
0
8
0
0
0
0
0
77
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
39
0
0
0
8
0
0
0
0
24
8
0
8
0
0
% I
% Lys:
0
0
0
0
24
0
70
0
0
0
0
0
0
0
0
% K
% Leu:
16
8
8
0
0
0
0
0
16
0
0
77
0
8
16
% L
% Met:
0
16
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
77
0
0
0
0
8
0
0
8
0
24
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
54
77
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
8
77
0
0
0
16
62
0
0
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
8
0
85
62
0
0
0
0
0
% V
% Trp:
8
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
0
8
0
8
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _