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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTNS All Species: 19.09
Human Site: S203 Identified Species: 35
UniProt: O60931 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60931 NP_004928 367 41738 S203 N G V N P V N S N D V F F S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089732 367 41660 S203 N G V N P V N S N D V F F S L
Dog Lupus familis XP_548340 367 41826 S203 N G V N P V D S N D V F F S L
Cat Felis silvestris
Mouse Mus musculus P57757 367 42185 S203 N G V N P V D S N D A F F S L
Rat Rattus norvegicus XP_001080248 367 41895 I203 N G V N P V D I N D A F F S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508868 605 66131 S441 N G V N P V D S N D V F F S L
Chicken Gallus gallus
Frog Xenopus laevis NP_001084886 375 42407 A212 N G V F P V E A N D V F F S L
Zebra Danio Brachydanio rerio NP_001018407 384 43736 A208 N G V I P V D A N D V F F S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCR7 397 44570 L208 L G V N P V M L N D V V F S L
Honey Bee Apis mellifera XP_394902 297 34497 C136 T V I T I I Q C F I Y E I G N
Nematode Worm Caenorhab. elegans Q09500 404 45376 L205 R S P P P V L L N D V V F A V
Sea Urchin Strong. purpuratus XP_001199518 324 35859 Y163 L N F D F L A Y N I T G F V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17261 260 30098 V99 V V L L T Q V V A G A R I W R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.7 84.7 N.A. 84.1 82 N.A. 46.1 N.A. 61.8 57.8 N.A. 39.7 42.2 34.1 42.7
Protein Similarity: 100 N.A. 98.9 91.8 N.A. 91.8 91.2 N.A. 53.3 N.A. 76 75.2 N.A. 57.9 58.5 50.2 58
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 80 N.A. 93.3 N.A. 80 80 N.A. 73.3 0 40 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 86.6 N.A. 100 N.A. 86.6 93.3 N.A. 73.3 13.3 53.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 16 8 0 24 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 39 0 0 77 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 8 8 8 0 0 0 8 0 0 62 85 0 0 % F
% Gly: 0 70 0 0 0 0 0 0 0 8 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 8 8 0 8 0 16 0 0 16 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 0 8 8 0 8 8 16 0 0 0 0 0 0 70 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 62 8 0 54 0 0 16 0 85 0 0 0 0 0 8 % N
% Pro: 0 0 8 8 77 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % R
% Ser: 0 8 0 0 0 0 0 39 0 0 0 0 0 70 0 % S
% Thr: 8 0 0 8 8 0 0 0 0 0 8 0 0 0 0 % T
% Val: 8 16 70 0 0 77 8 8 0 0 62 16 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _