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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNS
All Species:
32.42
Human Site:
S234
Identified Species:
59.44
UniProt:
O60931
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60931
NP_004928
367
41738
S234
E
R
G
G
Q
R
V
S
W
P
A
I
G
F
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089732
367
41660
S234
E
R
G
G
Q
R
V
S
W
P
A
V
G
F
L
Dog
Lupus familis
XP_548340
367
41826
S234
E
R
G
T
Q
H
V
S
W
P
A
I
S
F
L
Cat
Felis silvestris
Mouse
Mus musculus
P57757
367
42185
S234
E
R
G
N
Q
R
V
S
W
P
S
I
G
F
L
Rat
Rattus norvegicus
XP_001080248
367
41895
S234
E
R
G
N
Q
R
V
S
R
P
S
I
G
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508868
605
66131
S472
E
R
G
D
Q
K
V
S
P
L
A
I
G
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084886
375
42407
S243
E
R
G
S
Q
T
V
S
K
V
A
I
G
L
L
Zebra Danio
Brachydanio rerio
NP_001018407
384
43736
S239
E
R
G
G
Q
K
V
S
K
V
A
I
G
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCR7
397
44570
S239
Q
R
A
Q
Q
R
V
S
F
I
A
Y
G
I
L
Honey Bee
Apis mellifera
XP_394902
297
34497
L167
F
I
L
I
S
I
I
L
A
I
A
N
V
I
T
Nematode Worm
Caenorhab. elegans
Q09500
404
45376
S236
E
R
D
N
Q
S
V
S
S
K
C
I
A
L
M
Sea Urchin
Strong. purpuratus
XP_001199518
324
35859
Y194
A
Y
K
A
K
N
P
Y
G
V
N
P
V
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P17261
260
30098
F130
L
L
A
S
L
A
I
F
S
L
L
T
V
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
84.7
N.A.
84.1
82
N.A.
46.1
N.A.
61.8
57.8
N.A.
39.7
42.2
34.1
42.7
Protein Similarity:
100
N.A.
98.9
91.8
N.A.
91.8
91.2
N.A.
53.3
N.A.
76
75.2
N.A.
57.9
58.5
50.2
58
P-Site Identity:
100
N.A.
93.3
80
N.A.
86.6
80
N.A.
73.3
N.A.
66.6
73.3
N.A.
53.3
6.6
40
6.6
P-Site Similarity:
100
N.A.
100
80
N.A.
93.3
86.6
N.A.
80
N.A.
66.6
80
N.A.
66.6
13.3
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
0
8
0
0
8
0
62
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
8
0
0
0
0
47
8
% F
% Gly:
0
0
62
24
0
0
0
0
8
0
0
0
62
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
8
16
0
0
16
0
62
0
16
0
% I
% Lys:
0
0
8
0
8
16
0
0
16
8
0
0
0
0
0
% K
% Leu:
8
8
8
0
8
0
0
8
0
16
8
0
0
31
77
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
24
0
8
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
39
0
8
0
0
0
% P
% Gln:
8
0
0
8
77
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
77
0
0
0
39
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
16
8
8
0
77
16
0
16
0
8
0
0
% S
% Thr:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
8
% T
% Val:
0
0
0
0
0
0
77
0
0
24
0
8
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _