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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTNS All Species: 20.3
Human Site: S39 Identified Species: 37.22
UniProt: O60931 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60931 NP_004928 367 41738 S39 V K L E N G S S T N V S L T L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089732 367 41660 S39 V K L E N G S S T N V S I A L
Dog Lupus familis XP_548340 367 41826 S39 V E L E N G S S A N T S I I L
Cat Felis silvestris
Mouse Mus musculus P57757 367 42185 S39 V K L E N G S S T N V D I T L
Rat Rattus norvegicus XP_001080248 367 41895 S39 V K L V N G S S T N V S I T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508868 605 66131 S277 V T L E N G S S T N V S I Q L
Chicken Gallus gallus
Frog Xenopus laevis NP_001084886 375 42407 F48 V A L Q N G S F K N I S I T V
Zebra Danio Brachydanio rerio NP_001018407 384 43736 I44 Q E F S S E N I T I T L S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCR7 397 44570 E44 T V L L N S N E T F L V F A N
Honey Bee Apis mellifera XP_394902 297 34497
Nematode Worm Caenorhab. elegans Q09500 404 45376 N41 I G G E V S V N F Q I K N H T
Sea Urchin Strong. purpuratus XP_001199518 324 35859
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17261 260 30098
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.7 84.7 N.A. 84.1 82 N.A. 46.1 N.A. 61.8 57.8 N.A. 39.7 42.2 34.1 42.7
Protein Similarity: 100 N.A. 98.9 91.8 N.A. 91.8 91.2 N.A. 53.3 N.A. 76 75.2 N.A. 57.9 58.5 50.2 58
P-Site Identity: 100 N.A. 86.6 66.6 N.A. 86.6 86.6 N.A. 80 N.A. 53.3 6.6 N.A. 20 0 6.6 0
P-Site Similarity: 100 N.A. 93.3 80 N.A. 93.3 93.3 N.A. 86.6 N.A. 80 33.3 N.A. 33.3 0 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 8 0 0 0 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 16 0 47 0 8 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 8 8 8 0 0 8 0 0 % F
% Gly: 0 8 8 0 0 54 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 0 0 0 0 0 8 0 8 16 0 47 8 0 % I
% Lys: 0 31 0 0 0 0 0 0 8 0 0 8 0 0 0 % K
% Leu: 0 0 62 8 0 0 0 0 0 0 8 8 8 0 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 62 0 16 8 0 54 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 8 0 0 8 0 0 0 0 0 8 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 8 16 54 47 0 0 0 47 8 8 0 % S
% Thr: 8 8 0 0 0 0 0 0 54 0 16 0 0 31 8 % T
% Val: 54 8 0 8 8 0 8 0 0 0 39 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _