KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNS
All Species:
23.64
Human Site:
Y100
Identified Species:
43.33
UniProt:
O60931
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60931
NP_004928
367
41738
Y100
N
V
G
Q
L
T
V
Y
L
H
G
N
H
S
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089732
367
41660
Y100
N
V
G
Q
V
T
V
Y
L
H
G
N
H
S
N
Dog
Lupus familis
XP_548340
367
41826
Y100
N
V
G
Q
V
T
V
Y
L
H
G
N
H
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P57757
367
42185
F100
N
I
G
Q
V
T
V
F
L
H
G
N
H
S
N
Rat
Rattus norvegicus
XP_001080248
367
41895
Y100
N
I
G
Q
V
T
V
Y
L
H
G
N
H
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508868
605
66131
Y338
A
V
G
Q
V
T
I
Y
L
Q
S
N
N
S
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084886
375
42407
Y109
H
V
G
Q
V
T
A
Y
L
Q
S
N
V
S
H
Zebra Danio
Brachydanio rerio
NP_001018407
384
43736
S105
G
Q
V
T
A
Y
L
S
S
N
D
T
H
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCR7
397
44570
S105
N
V
K
V
V
A
D
S
D
D
A
N
K
E
I
Honey Bee
Apis mellifera
XP_394902
297
34497
S33
V
R
V
T
V
E
K
S
D
I
L
Y
H
I
S
Nematode Worm
Caenorhab. elegans
Q09500
404
45376
G102
A
L
N
C
T
T
D
G
S
I
T
C
P
L
D
Sea Urchin
Strong. purpuratus
XP_001199518
324
35859
K60
Q
I
E
L
F
N
D
K
Y
E
I
A
S
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P17261
260
30098
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
84.7
N.A.
84.1
82
N.A.
46.1
N.A.
61.8
57.8
N.A.
39.7
42.2
34.1
42.7
Protein Similarity:
100
N.A.
98.9
91.8
N.A.
91.8
91.2
N.A.
53.3
N.A.
76
75.2
N.A.
57.9
58.5
50.2
58
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
80
86.6
N.A.
60
N.A.
53.3
6.6
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
80
N.A.
73.3
20
N.A.
26.6
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
8
8
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
24
0
16
8
8
0
0
0
8
% D
% Glu:
0
0
8
0
0
8
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
54
0
0
0
0
8
0
0
39
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
39
0
0
54
0
8
% H
% Ile:
0
24
0
0
0
0
8
0
0
16
8
0
0
24
8
% I
% Lys:
0
0
8
0
0
0
8
8
0
0
0
0
8
0
8
% K
% Leu:
0
8
0
8
8
0
8
0
54
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
0
8
0
0
8
0
0
0
8
0
62
8
0
47
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% P
% Gln:
8
8
0
54
0
0
0
0
0
16
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
24
16
0
16
0
8
54
8
% S
% Thr:
0
0
0
16
8
62
0
0
0
0
8
8
0
0
0
% T
% Val:
8
47
16
8
62
0
39
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
47
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _