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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNS
All Species:
25.45
Human Site:
Y194
Identified Species:
46.67
UniProt:
O60931
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60931
NP_004928
367
41738
Y194
K
E
Q
F
L
L
K
Y
P
N
G
V
N
P
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089732
367
41660
Y194
K
E
Q
F
L
L
K
Y
P
N
G
V
N
P
V
Dog
Lupus familis
XP_548340
367
41826
Y194
K
E
Q
F
F
L
K
Y
P
N
G
V
N
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P57757
367
42185
Y194
Q
E
E
F
L
L
K
Y
P
N
G
V
N
P
V
Rat
Rattus norvegicus
XP_001080248
367
41895
Y194
Q
E
E
F
L
L
K
Y
P
N
G
V
N
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508868
605
66131
H432
K
E
Q
F
L
H
Q
H
P
N
G
V
N
P
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084886
375
42407
Y203
K
E
Q
F
L
V
V
Y
P
N
G
V
F
P
V
Zebra Danio
Brachydanio rerio
NP_001018407
384
43736
D199
Q
E
E
F
L
K
K
D
P
N
G
V
I
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCR7
397
44570
Y199
Q
N
E
Y
E
V
R
Y
P
L
G
V
N
P
V
Honey Bee
Apis mellifera
XP_394902
297
34497
F127
F
F
A
L
H
A
T
F
A
T
V
I
T
I
I
Nematode Worm
Caenorhab. elegans
Q09500
404
45376
N196
K
N
E
Y
N
I
V
N
P
R
S
P
P
P
V
Sea Urchin
Strong. purpuratus
XP_001199518
324
35859
I154
N
I
K
R
K
S
V
I
G
L
N
F
D
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P17261
260
30098
M90
Y
C
L
H
G
C
L
M
N
V
V
L
L
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
84.7
N.A.
84.1
82
N.A.
46.1
N.A.
61.8
57.8
N.A.
39.7
42.2
34.1
42.7
Protein Similarity:
100
N.A.
98.9
91.8
N.A.
91.8
91.2
N.A.
53.3
N.A.
76
75.2
N.A.
57.9
58.5
50.2
58
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
80
N.A.
80
66.6
N.A.
46.6
0
26.6
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
80
20
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
0
62
39
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
62
8
0
0
8
0
0
0
8
8
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
70
0
0
0
0
% G
% His:
0
0
0
8
8
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
8
0
0
0
8
8
8
8
% I
% Lys:
47
0
8
0
8
8
47
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
54
39
8
0
0
16
0
8
8
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
16
0
0
8
0
0
8
8
62
8
0
54
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
77
0
0
8
8
77
0
% P
% Gln:
31
0
39
0
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
0
0
8
8
0
% T
% Val:
0
0
0
0
0
16
24
0
0
8
16
70
0
0
77
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
16
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _