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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNS
All Species:
18.48
Human Site:
Y291
Identified Species:
33.89
UniProt:
O60931
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60931
NP_004928
367
41738
Y291
Q
A
Y
M
N
F
Y
Y
K
S
T
E
G
W
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089732
367
41660
Y291
Q
A
Y
M
N
F
H
Y
K
S
T
E
G
W
S
Dog
Lupus familis
XP_548340
367
41826
Y291
Q
A
Y
M
N
F
H
Y
K
S
T
E
G
W
S
Cat
Felis silvestris
Mouse
Mus musculus
P57757
367
42185
Y291
Q
A
Y
M
N
F
Y
Y
K
S
T
K
G
W
S
Rat
Rattus norvegicus
XP_001080248
367
41895
Y291
Q
A
Y
M
N
F
Y
Y
K
S
T
K
G
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508868
605
66131
R529
Q
A
Y
M
N
F
R
R
K
S
T
E
G
W
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084886
375
42407
R300
Q
A
Y
M
N
F
H
R
K
S
T
E
G
W
S
Zebra Danio
Brachydanio rerio
NP_001018407
384
43736
R296
Q
A
H
M
N
Y
R
R
K
S
T
E
G
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCR7
397
44570
R296
Q
A
L
M
N
Y
R
R
K
S
T
S
G
W
S
Honey Bee
Apis mellifera
XP_394902
297
34497
G222
I
F
L
D
F
T
G
G
M
L
S
M
L
Q
M
Nematode Worm
Caenorhab. elegans
Q09500
404
45376
R293
Q
A
Y
F
N
Y
T
R
K
S
T
V
G
W
S
Sea Urchin
Strong. purpuratus
XP_001199518
324
35859
T249
M
W
L
F
A
L
I
T
L
I
I
T
A
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P17261
260
30098
C185
S
T
R
K
S
M
D
C
F
P
I
Q
G
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
84.7
N.A.
84.1
82
N.A.
46.1
N.A.
61.8
57.8
N.A.
39.7
42.2
34.1
42.7
Protein Similarity:
100
N.A.
98.9
91.8
N.A.
91.8
91.2
N.A.
53.3
N.A.
76
75.2
N.A.
57.9
58.5
50.2
58
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
86.6
73.3
N.A.
66.6
0
66.6
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
93.3
86.6
N.A.
73.3
6.6
73.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
0
8
0
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% E
% Phe:
0
8
0
16
8
54
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
8
0
0
0
0
85
0
0
% G
% His:
0
0
8
0
0
0
24
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
8
16
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
77
0
0
16
0
0
0
% K
% Leu:
0
0
24
0
0
8
0
0
8
8
0
0
8
0
0
% L
% Met:
8
0
0
70
0
8
0
0
8
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
77
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
8
0
0
0
24
39
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
0
0
0
77
8
8
0
0
85
% S
% Thr:
0
8
0
0
0
8
8
8
0
0
77
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
77
0
% W
% Tyr:
0
0
62
0
0
24
24
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _