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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTNB
All Species:
21.52
Human Site:
S77
Identified Species:
43.03
UniProt:
O60941
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60941
NP_068707.1
627
71356
S77
L
D
H
T
T
E
I
S
V
S
R
L
E
T
V
Chimpanzee
Pan troglodytes
XP_515336
627
71305
S77
L
D
H
T
T
E
I
S
V
S
R
L
E
T
V
Rhesus Macaque
Macaca mulatta
XP_001102769
743
83913
N77
L
D
P
N
I
E
L
N
V
S
R
L
E
A
V
Dog
Lupus familis
XP_540111
670
76530
S77
L
D
H
S
T
E
I
S
V
S
R
L
E
T
V
Cat
Felis silvestris
Mouse
Mus musculus
O70585
700
78337
S77
L
D
H
S
T
E
I
S
V
S
R
L
E
T
V
Rat
Rattus norvegicus
P84060
654
73859
S77
L
D
H
A
T
E
I
S
V
S
R
L
E
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515697
743
83772
N77
L
D
P
N
V
E
L
N
V
A
R
L
E
A
V
Chicken
Gallus gallus
XP_419187
742
83445
N77
L
D
P
S
I
E
L
N
V
A
R
L
E
A
V
Frog
Xenopus laevis
NP_001079191
743
83797
N77
V
D
P
N
V
E
L
N
V
A
R
L
E
A
V
Zebra Danio
Brachydanio rerio
A2CI97
648
73379
V62
I
S
L
A
Q
E
D
V
Q
Q
H
L
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9Y048
590
65408
K98
L
P
L
H
T
V
I
K
T
S
R
A
E
L
L
Sea Urchin
Strong. purpuratus
XP_797247
727
82017
S68
M
S
L
S
D
E
L
S
M
S
R
V
E
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
64
89.5
N.A.
84
88.6
N.A.
64
64.4
64.1
21.4
N.A.
N.A.
N.A.
42.5
37.9
Protein Similarity:
100
100
74.2
91.7
N.A.
86.1
90.5
N.A.
74
73.8
74.6
40.4
N.A.
N.A.
N.A.
60.1
55.3
P-Site Identity:
100
100
60
93.3
N.A.
93.3
93.3
N.A.
53.3
53.3
46.6
20
N.A.
N.A.
N.A.
40
40
P-Site Similarity:
100
100
73.3
100
N.A.
100
93.3
N.A.
73.3
80
73.3
33.3
N.A.
N.A.
N.A.
46.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
0
25
0
9
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
9
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
92
0
0
0
0
0
0
100
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
42
9
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
17
0
50
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
75
0
25
0
0
0
42
0
0
0
0
84
0
9
17
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
0
0
0
34
0
0
0
0
0
0
0
% N
% Pro:
0
9
34
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% R
% Ser:
0
17
0
34
0
0
0
50
0
67
0
0
0
0
0
% S
% Thr:
0
0
0
17
50
0
0
0
9
0
0
0
0
50
0
% T
% Val:
9
0
0
0
17
9
0
9
75
0
0
9
0
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _