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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTNB
All Species:
19.39
Human Site:
Y363
Identified Species:
38.79
UniProt:
O60941
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60941
NP_068707.1
627
71356
Y363
T
P
T
K
R
L
Q
Y
S
Q
D
I
P
S
H
Chimpanzee
Pan troglodytes
XP_515336
627
71305
Y363
T
P
T
K
R
L
Q
Y
S
Q
D
I
P
S
H
Rhesus Macaque
Macaca mulatta
XP_001102769
743
83913
S395
K
G
K
G
I
Q
Y
S
L
N
V
A
D
R
L
Dog
Lupus familis
XP_540111
670
76530
Y363
T
P
T
K
R
L
Q
Y
S
Q
D
I
P
S
H
Cat
Felis silvestris
Mouse
Mus musculus
O70585
700
78337
Y363
T
P
T
K
R
L
Q
Y
S
Q
D
M
P
N
L
Rat
Rattus norvegicus
P84060
654
73859
Y363
T
P
T
K
R
L
Q
Y
G
Q
D
M
P
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515697
743
83772
S395
K
G
K
G
L
Q
Y
S
L
D
V
A
D
R
L
Chicken
Gallus gallus
XP_419187
742
83445
S394
K
G
K
G
L
Q
Y
S
L
D
V
A
D
R
L
Frog
Xenopus laevis
NP_001079191
743
83797
S392
K
G
K
G
L
Q
Y
S
L
G
V
A
D
R
L
Zebra Danio
Brachydanio rerio
A2CI97
648
73379
E362
S
K
S
L
Q
T
E
E
I
Q
I
P
Q
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9Y048
590
65408
T372
N
I
V
P
A
T
P
T
T
I
R
R
Q
H
A
Sea Urchin
Strong. purpuratus
XP_797247
727
82017
T345
D
S
T
R
I
L
R
T
E
E
D
F
K
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
64
89.5
N.A.
84
88.6
N.A.
64
64.4
64.1
21.4
N.A.
N.A.
N.A.
42.5
37.9
Protein Similarity:
100
100
74.2
91.7
N.A.
86.1
90.5
N.A.
74
73.8
74.6
40.4
N.A.
N.A.
N.A.
60.1
55.3
P-Site Identity:
100
100
0
100
N.A.
80
73.3
N.A.
0
0
0
6.6
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
100
100
0
100
N.A.
93.3
86.6
N.A.
0
0
0
33.3
N.A.
N.A.
N.A.
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
34
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
17
50
0
34
0
0
% D
% Glu:
0
0
0
0
0
0
9
9
9
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
34
0
34
0
0
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
25
% H
% Ile:
0
9
0
0
17
0
0
0
9
9
9
25
0
0
0
% I
% Lys:
34
9
34
42
0
0
0
0
0
0
0
0
9
9
0
% K
% Leu:
0
0
0
9
25
50
0
0
34
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
9
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
0
17
0
% N
% Pro:
0
42
0
9
0
0
9
0
0
0
0
9
42
0
0
% P
% Gln:
0
0
0
0
9
34
42
0
0
50
0
0
17
0
0
% Q
% Arg:
0
0
0
9
42
0
9
0
0
0
9
9
0
42
0
% R
% Ser:
9
9
9
0
0
0
0
34
34
0
0
0
0
25
0
% S
% Thr:
42
0
50
0
0
17
0
17
9
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
34
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _