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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNGTT All Species: 42.73
Human Site: S275 Identified Species: 85.45
UniProt: O60942 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60942 NP_003791.3 597 68557 S275 F P G A Q P V S M D K Q N I K
Chimpanzee Pan troglodytes XP_518633 688 77346 S366 F P G A Q P V S M D K Q N I K
Rhesus Macaque Macaca mulatta XP_001090617 682 76905 E239 C P T T E N T E T F I R L C E
Dog Lupus familis XP_539035 707 79921 S385 F P G A Q P V S M D K Q N I K
Cat Felis silvestris
Mouse Mus musculus O55236 597 68665 S275 F P G A Q P V S M D K Q N I R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513473 621 71390 S299 F P G A Q P V S M D K Q N I K
Chicken Gallus gallus XP_419843 600 68857 S278 F P G A Q P V S M D K Q N I K
Frog Xenopus laevis NP_001084232 598 68804 S276 F P G T Q P V S M D K N N I K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572952 649 74692 S310 F P G A Q P V S M D R E N I K
Honey Bee Apis mellifera XP_397436 924 105676 S282 F P G S Q P V S M D E D N I R
Nematode Worm Caenorhab. elegans Q17607 623 72110 S292 F P G L Q P V S L S R G N I N
Sea Urchin Strong. purpuratus XP_782740 613 69553 S264 F P G S Q P V S M D R N N I N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.7 75.3 83 N.A. 94.9 N.A. N.A. 88.2 88.3 81.6 N.A. N.A. 46.6 36.4 40.1 55.1
Protein Similarity: 100 86.4 77.4 83.8 N.A. 97.4 N.A. N.A. 92.2 94.1 90.6 N.A. N.A. 62.8 46.5 57.4 70.4
P-Site Identity: 100 100 6.6 100 N.A. 93.3 N.A. N.A. 100 100 86.6 N.A. N.A. 86.6 73.3 60 73.3
P-Site Similarity: 100 100 26.6 100 N.A. 100 N.A. N.A. 100 100 86.6 N.A. N.A. 100 93.3 73.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 84 0 9 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 9 0 0 9 9 0 0 9 % E
% Phe: 92 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 92 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 92 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 59 0 0 0 59 % K
% Leu: 0 0 0 9 0 0 0 0 9 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 17 92 0 17 % N
% Pro: 0 100 0 0 0 92 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 92 0 0 0 0 0 0 50 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 25 9 0 0 17 % R
% Ser: 0 0 0 17 0 0 0 92 0 9 0 0 0 0 0 % S
% Thr: 0 0 9 17 0 0 9 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _