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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
11.82
Human Site:
S24
Identified Species:
18.57
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
S24
A
F
E
K
R
R
H
S
A
I
L
I
R
P
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
S24
A
F
E
K
R
R
Q
S
A
I
L
I
R
P
L
Dog
Lupus familis
XP_549087
752
82813
V24
S
L
E
K
R
R
L
V
V
F
L
I
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
S24
A
F
E
K
H
K
H
S
A
V
L
T
R
A
L
Rat
Rattus norvegicus
Q704E8
752
82539
S24
A
F
E
K
H
K
H
S
A
V
L
T
R
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
A143
F
G
E
R
P
F
K
A
F
I
K
C
Y
K
A
Chicken
Gallus gallus
XP_420301
742
81302
A24
A
L
L
R
P
P
A
A
A
A
C
A
H
G
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
R25
K
L
S
L
L
L
Q
R
S
S
A
V
Q
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
P31
C
Y
T
L
A
K
G
P
G
T
H
V
Q
A
R
Honey Bee
Apis mellifera
XP_396202
744
83257
Q35
C
S
I
K
S
R
K
Q
I
I
Y
Y
E
G
I
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
Y23
T
I
R
S
Q
A
V
Y
R
S
F
S
S
L
T
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
R25
I
F
Q
S
I
S
H
R
N
V
Q
L
S
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
K25
V
N
L
Q
P
Q
P
K
I
P
S
F
S
Y
S
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
K17
I
G
R
I
V
R
S
K
F
R
S
G
L
I
R
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
L24
A
H
G
T
S
A
L
L
R
R
P
R
L
W
A
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
93.3
60
N.A.
66.6
66.6
N.A.
13.3
13.3
N.A.
0
N.A.
0
20
0
13.3
P-Site Similarity:
100
N.A.
93.3
66.6
N.A.
80
80
N.A.
26.6
26.6
N.A.
20
N.A.
26.6
26.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
7
14
7
14
34
7
7
7
0
20
14
% A
% Cys:
14
0
0
0
0
0
0
0
0
0
7
7
0
7
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
40
0
0
0
0
0
0
0
0
0
7
0
0
% E
% Phe:
7
34
0
0
0
7
0
0
14
7
7
7
0
0
0
% F
% Gly:
0
14
7
0
0
0
7
0
7
0
0
7
0
14
0
% G
% His:
0
7
0
0
14
0
27
0
0
0
7
0
7
0
0
% H
% Ile:
14
7
7
7
7
0
0
0
14
27
0
20
0
7
7
% I
% Lys:
7
0
0
40
0
20
14
14
0
0
7
0
0
7
0
% K
% Leu:
0
20
14
14
7
7
14
7
0
0
34
7
14
7
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
7
7
7
0
7
7
0
0
20
0
% P
% Gln:
0
0
7
7
7
7
14
7
0
0
7
0
14
0
0
% Q
% Arg:
0
0
14
14
20
34
0
14
14
14
0
7
34
0
14
% R
% Ser:
7
7
7
14
14
7
7
27
7
14
14
7
20
7
14
% S
% Thr:
7
0
7
7
0
0
0
0
0
7
0
14
0
0
7
% T
% Val:
7
0
0
0
7
0
7
7
7
20
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
14
% W
% Tyr:
0
7
0
0
0
0
0
7
0
0
7
7
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _