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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
48.79
Human Site:
S250
Identified Species:
76.67
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
S250
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
S251
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Dog
Lupus familis
XP_549087
752
82813
S250
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
S250
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Rat
Rattus norvegicus
Q704E8
752
82539
S250
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
S369
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Chicken
Gallus gallus
XP_420301
742
81302
S239
S
R
Q
T
G
A
L
S
K
T
I
D
R
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
S241
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
S263
N
K
Q
T
G
A
L
S
K
T
I
D
R
G
S
Honey Bee
Apis mellifera
XP_396202
744
83257
S267
S
R
Q
T
G
A
L
S
K
T
I
D
R
G
S
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
V226
G
T
R
G
M
S
F
V
L
S
S
L
I
F
N
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
S248
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
R248
H
L
H
D
L
D
L
R
Y
H
L
S
R
E
T
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
M218
T
G
G
L
T
R
A
M
D
R
G
T
K
G
I
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
T228
S
K
Q
T
G
G
L
T
R
A
I
D
R
G
T
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
N.A.
73.3
86.6
0
93.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
N.A.
93.3
93.3
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
74
7
0
0
60
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
0
0
7
0
0
80
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% F
% Gly:
7
7
7
7
80
7
0
0
0
0
7
0
0
87
0
% G
% His:
7
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
80
0
7
0
7
% I
% Lys:
0
14
0
0
0
0
0
0
74
0
0
0
7
0
0
% K
% Leu:
0
7
0
7
7
0
87
0
7
0
7
7
0
0
0
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
7
0
0
7
0
7
7
7
0
0
87
0
0
% R
% Ser:
74
0
0
0
0
7
0
74
0
7
7
7
0
0
20
% S
% Thr:
7
7
0
80
7
0
0
7
0
20
0
7
0
0
67
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _