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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
13.94
Human Site:
S461
Identified Species:
21.9
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
S461
I
K
D
K
V
M
A
S
P
L
Q
I
T
P
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
S462
I
K
D
K
V
M
A
S
P
L
Q
I
T
P
Q
Dog
Lupus familis
XP_549087
752
82813
S461
I
K
D
K
A
M
A
S
P
I
Q
I
T
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
P461
I
K
D
K
V
M
A
P
P
L
Q
I
T
P
Q
Rat
Rattus norvegicus
Q704E8
752
82539
S461
I
K
D
K
A
M
A
S
P
L
Q
I
T
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
A580
I
K
D
R
V
M
A
A
P
L
Q
I
T
P
Q
Chicken
Gallus gallus
XP_420301
742
81302
P450
I
K
D
K
E
L
A
P
P
L
Q
I
T
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
P452
I
K
E
K
E
M
A
P
P
L
I
V
T
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
Q474
I
Q
T
A
A
N
A
Q
P
L
F
V
D
T
T
Honey Bee
Apis mellifera
XP_396202
744
83257
S473
T
M
D
T
A
I
K
S
K
E
N
A
M
K
F
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
N431
K
R
L
E
I
V
D
N
D
I
S
L
K
F
E
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
P459
I
K
S
Q
I
N
A
P
A
L
Q
I
A
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
M453
S
L
V
D
M
K
S
M
F
Q
L
L
E
E
K
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
A422
N
E
V
K
I
K
N
A
E
R
P
L
M
L
P
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
K439
I
K
E
Q
P
N
A
K
P
L
T
L
T
R
G
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
86.6
80
N.A.
66.6
N.A.
26.6
13.3
0
53.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
100
86.6
N.A.
80
N.A.
40
20
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
27
0
74
14
7
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
7
0
0
7
0
7
0
0
0
7
0
0
% D
% Glu:
0
7
14
7
14
0
0
0
7
7
0
0
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
7
0
0
7
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
74
0
0
0
20
7
0
0
0
14
7
54
0
0
0
% I
% Lys:
7
67
0
54
0
14
7
7
7
0
0
0
7
7
7
% K
% Leu:
0
7
7
0
0
7
0
0
0
67
7
27
0
7
0
% L
% Met:
0
7
0
0
7
47
0
7
0
0
0
0
14
0
0
% M
% Asn:
7
0
0
0
0
20
7
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
27
67
0
7
0
0
60
7
% P
% Gln:
0
7
0
14
0
0
0
7
0
7
54
0
0
0
60
% Q
% Arg:
0
7
0
7
0
0
0
0
0
7
0
0
0
7
0
% R
% Ser:
7
0
7
0
0
0
7
34
0
0
7
0
0
0
0
% S
% Thr:
7
0
7
7
0
0
0
0
0
0
7
0
60
7
7
% T
% Val:
0
0
14
0
27
7
0
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _