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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
17.27
Human Site:
S572
Identified Species:
27.14
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
S572
N
L
L
Y
G
N
I
S
A
S
P
E
E
V
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
S573
N
L
L
Y
G
N
I
S
A
S
P
E
E
V
Y
Dog
Lupus familis
XP_549087
752
82813
H572
N
L
L
Y
G
N
I
H
A
S
P
E
E
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
N572
N
L
L
Y
G
N
I
N
A
S
P
E
E
V
Y
Rat
Rattus norvegicus
Q704E8
752
82539
N572
N
L
L
Y
G
N
I
N
A
S
P
E
E
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
S691
N
L
L
Y
G
N
I
S
A
A
P
E
N
V
Y
Chicken
Gallus gallus
XP_420301
742
81302
S561
N
L
L
Y
G
N
I
S
A
T
P
E
E
V
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
N563
N
L
M
Y
G
N
I
N
A
T
A
E
D
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
G582
I
E
H
N
I
H
Y
G
N
L
S
K
S
H
A
Honey Bee
Apis mellifera
XP_396202
744
83257
L583
H
E
S
I
F
Y
N
L
H
Y
G
N
L
S
K
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
E539
G
R
P
S
A
S
M
E
E
V
Y
Q
A
A
K
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
D570
N
L
Q
Y
G
K
L
D
A
T
A
E
E
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
D561
S
I
G
V
V
P
Q
D
T
V
L
F
N
D
T
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
V530
N
D
T
I
W
E
N
V
K
F
G
R
I
D
A
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
S549
N
I
R
Y
G
N
L
S
A
T
P
E
Q
V
I
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
66.6
N.A.
0
0
0
53.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
93.3
100
N.A.
93.3
N.A.
13.3
6.6
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
67
7
14
0
7
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
14
0
0
0
0
7
14
0
% D
% Glu:
0
14
0
0
0
7
0
7
7
0
0
67
47
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
7
0
7
0
0
7
% F
% Gly:
7
0
7
0
67
0
0
7
0
0
14
0
0
0
0
% G
% His:
7
0
7
0
0
7
0
7
7
0
0
0
0
7
0
% H
% Ile:
7
14
0
14
7
0
54
0
0
0
0
0
7
0
7
% I
% Lys:
0
0
0
0
0
7
0
0
7
0
0
7
0
0
14
% K
% Leu:
0
60
47
0
0
0
14
7
0
7
7
0
7
0
0
% L
% Met:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
74
0
0
7
0
60
14
20
7
0
0
7
14
0
0
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
7
0
0
0
0
7
7
0
0
% Q
% Arg:
0
7
7
0
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
7
0
7
7
0
7
0
34
0
34
7
0
7
7
0
% S
% Thr:
0
0
7
0
0
0
0
0
7
27
0
0
0
0
7
% T
% Val:
0
0
0
7
7
0
0
7
0
14
0
0
0
67
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
0
7
7
0
0
7
7
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _