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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB7 All Species: 6.06
Human Site: S63 Identified Species: 9.52
UniProt: O75027 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75027 NP_004290.2 752 82641 S63 Q I P E S L K S I T W Q R L G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097352 753 82871 K63 Q Q I P E S L K S I T W Q R L
Dog Lupus familis XP_549087 752 82813 Y63 Q I P E S L R Y T T W Q R L G
Cat Felis silvestris
Mouse Mus musculus Q61102 752 82576 N63 Q T T E S L R N T T Q Q R W G
Rat Rattus norvegicus Q704E8 752 82539 N63 Q T T E S L R N S T Q Q R W E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506747 870 95638 A182 Q V Q W L D R A R F R D G F W
Chicken Gallus gallus XP_420301 742 81302 S63 Q S L M G G H S R P L L E I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694879 743 82284 N64 E S S T W A N N R G Q N S Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728642 743 80448 K70 F T P T P G S K L L G G V F G
Honey Bee Apis mellifera XP_396202 744 83257 N74 D H T Q K K K N I L Q S K S I
Nematode Worm Caenorhab. elegans NP_001021830 704 77438 G62 T R T C F H P G A S S Q V P L
Sea Urchin Strong. purpuratus XP_001187214 731 80523 D64 T H K K S D L D N P Y W Q Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVM1 728 80402 D64 V I N A F L S D N S P S P S P
Baker's Yeast Sacchar. cerevisiae P40416 690 77504 K56 N L W N Q A Q K D I T H K K S
Red Bread Mold Neurospora crassa Q7RX59 716 78739 S63 R L F A P N G S A K D E S K P
Conservation
Percent
Protein Identity: 100 N.A. 99 92.6 N.A. 92.1 92.5 N.A. 73.7 78.8 N.A. 74.4 N.A. 51.5 53.1 49.8 54.6
Protein Similarity: 100 N.A. 99.4 94.9 N.A. 95.7 95.6 N.A. 79.1 87.2 N.A. 85.9 N.A. 68.4 70.4 68.2 69.9
P-Site Identity: 100 N.A. 6.6 80 N.A. 53.3 46.6 N.A. 6.6 13.3 N.A. 0 N.A. 13.3 13.3 6.6 6.6
P-Site Similarity: 100 N.A. 13.3 86.6 N.A. 66.6 60 N.A. 26.6 20 N.A. 13.3 N.A. 20 33.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 46.9 42.5 45
Protein Similarity: N.A. N.A. N.A. 63.4 61.9 64.2
P-Site Identity: N.A. N.A. N.A. 13.3 0 6.6
P-Site Similarity: N.A. N.A. N.A. 20 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 14 0 7 14 0 0 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 14 0 14 7 0 7 7 0 0 0 % D
% Glu: 7 0 0 27 7 0 0 0 0 0 0 7 7 0 7 % E
% Phe: 7 0 7 0 14 0 0 0 0 7 0 0 0 14 0 % F
% Gly: 0 0 0 0 7 14 7 7 0 7 7 7 7 0 27 % G
% His: 0 14 0 0 0 7 7 0 0 0 0 7 0 0 0 % H
% Ile: 0 20 7 0 0 0 0 0 14 14 0 0 0 7 7 % I
% Lys: 0 0 7 7 7 7 14 20 0 7 0 0 14 14 7 % K
% Leu: 0 14 7 0 7 34 14 0 7 14 7 7 0 14 14 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 7 0 7 7 27 14 0 0 7 0 0 0 % N
% Pro: 0 0 20 7 14 0 7 0 0 14 7 0 7 7 14 % P
% Gln: 47 7 7 7 7 0 7 0 0 0 27 34 14 14 7 % Q
% Arg: 7 7 0 0 0 0 27 0 20 0 7 0 27 7 0 % R
% Ser: 0 14 7 0 34 7 14 20 14 14 7 14 14 14 14 % S
% Thr: 14 20 27 14 0 0 0 0 14 27 14 0 0 0 0 % T
% Val: 7 7 0 0 0 0 0 0 0 0 0 0 14 0 0 % V
% Trp: 0 0 7 7 7 0 0 0 0 0 14 14 0 14 7 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _