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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
12.73
Human Site:
S74
Identified Species:
20
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
S74
Q
R
L
G
K
G
N
S
G
Q
F
L
D
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
S74
W
Q
R
L
G
K
G
S
S
R
Q
F
L
D
A
Dog
Lupus familis
XP_549087
752
82813
S74
Q
R
L
G
K
G
N
S
R
Q
I
L
D
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
S74
Q
R
W
G
K
D
N
S
R
Q
L
L
D
A
T
Rat
Rattus norvegicus
Q704E8
752
82539
S74
Q
R
W
E
K
N
N
S
R
Q
L
L
D
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
S193
D
G
F
W
R
A
V
S
H
D
R
V
S
E
A
Chicken
Gallus gallus
XP_420301
742
81302
P74
L
E
I
S
A
I
S
P
S
L
Q
L
I
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
A75
N
S
Q
Q
I
L
E
A
V
K
H
L
H
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
K81
G
V
F
G
K
K
A
K
G
G
A
P
A
A
A
Honey Bee
Apis mellifera
XP_396202
744
83257
V85
S
K
S
I
V
T
S
V
K
I
P
L
I
I
S
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
G73
Q
V
P
L
Q
A
S
G
Q
L
S
G
Y
Q
L
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
H75
W
Q
Q
K
K
I
Y
H
S
I
S
K
Q
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
P75
S
P
S
P
S
P
S
P
I
R
F
V
Q
R
S
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
F67
H
K
K
S
V
E
Q
F
S
S
A
P
K
V
K
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
T74
E
S
K
P
A
V
S
T
V
P
K
T
T
G
R
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
13.3
73.3
N.A.
66.6
60
N.A.
13.3
6.6
N.A.
6.6
N.A.
33.3
6.6
6.6
6.6
P-Site Similarity:
100
N.A.
26.6
73.3
N.A.
66.6
66.6
N.A.
26.6
20
N.A.
20
N.A.
33.3
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
14
7
7
0
0
14
0
7
27
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
0
0
7
0
0
27
7
0
% D
% Glu:
7
7
0
7
0
7
7
0
0
0
0
0
0
14
0
% E
% Phe:
0
0
14
0
0
0
0
7
0
0
14
7
0
0
0
% F
% Gly:
7
7
0
27
7
14
7
7
14
7
0
7
0
7
0
% G
% His:
7
0
0
0
0
0
0
7
7
0
7
0
7
0
0
% H
% Ile:
0
0
7
7
7
14
0
0
7
14
7
0
14
7
0
% I
% Lys:
0
14
14
7
40
14
0
7
7
7
7
7
7
0
14
% K
% Leu:
7
0
14
14
0
7
0
0
0
14
14
47
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
27
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
14
0
7
0
14
0
7
7
14
0
0
7
% P
% Gln:
34
14
14
7
7
0
7
0
7
27
14
0
14
14
7
% Q
% Arg:
0
27
7
0
7
0
0
0
20
14
7
0
0
7
7
% R
% Ser:
14
14
14
14
7
0
34
40
27
7
14
0
7
0
20
% S
% Thr:
0
0
0
0
0
7
0
7
0
0
0
7
7
0
14
% T
% Val:
0
14
0
0
14
7
7
7
14
0
0
14
0
14
0
% V
% Trp:
14
0
14
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _