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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
46.97
Human Site:
T246
Identified Species:
73.81
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
T246
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
T247
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Dog
Lupus familis
XP_549087
752
82813
T246
A
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
T246
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Rat
Rattus norvegicus
Q704E8
752
82539
T246
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
T365
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Chicken
Gallus gallus
XP_420301
742
81302
T235
A
F
H
L
S
R
Q
T
G
A
L
S
K
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
T237
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
T259
A
F
H
L
N
K
Q
T
G
A
L
S
K
T
I
Honey Bee
Apis mellifera
XP_396202
744
83257
T263
A
F
H
L
S
R
Q
T
G
A
L
S
K
T
I
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
G222
A
I
D
R
G
T
R
G
M
S
F
V
L
S
S
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
T244
S
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
D244
K
V
F
S
H
L
H
D
L
D
L
R
Y
H
L
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
L214
L
S
R
Q
T
G
G
L
T
R
A
M
D
R
G
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
T224
S
F
H
L
S
K
Q
T
G
G
L
T
R
A
I
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
86.6
N.A.
100
N.A.
73.3
86.6
0
93.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
86.6
N.A.
100
N.A.
86.6
86.6
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
0
0
74
7
0
0
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
7
0
7
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
80
7
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
40
0
0
0
7
7
7
7
80
7
0
0
0
0
7
% G
% His:
0
0
80
0
7
0
7
0
0
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
80
% I
% Lys:
7
0
0
0
0
14
0
0
0
0
0
0
74
0
0
% K
% Leu:
7
0
0
80
0
7
0
7
7
0
87
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
80
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
7
0
67
7
0
0
7
0
7
7
7
0
% R
% Ser:
14
7
0
7
74
0
0
0
0
7
0
74
0
7
7
% S
% Thr:
0
0
0
0
7
7
0
80
7
0
0
7
0
20
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _