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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
36.67
Human Site:
T446
Identified Species:
57.62
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
T446
I
D
M
N
T
L
F
T
L
L
K
V
D
T
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
T447
I
D
M
N
T
L
F
T
L
L
K
V
D
T
R
Dog
Lupus familis
XP_549087
752
82813
T446
I
D
M
N
T
L
F
T
L
L
K
V
D
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
T446
I
D
M
N
T
L
F
T
L
L
K
V
D
T
R
Rat
Rattus norvegicus
Q704E8
752
82539
T446
I
D
M
N
T
L
F
T
L
L
K
V
D
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
T565
I
D
M
N
T
L
F
T
L
L
K
V
D
A
Q
Chicken
Gallus gallus
XP_420301
742
81302
T435
I
D
M
N
T
L
F
T
L
L
S
V
D
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
T437
I
D
M
N
T
L
F
T
L
L
S
V
D
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
T459
L
D
M
R
A
M
F
T
L
M
N
V
D
S
S
Honey Bee
Apis mellifera
XP_396202
744
83257
M458
V
K
Q
A
F
I
D
M
Q
T
M
F
T
L
M
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
K416
S
L
L
T
L
K
P
K
I
V
E
A
A
D
A
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
N444
V
D
M
G
T
M
F
N
L
L
K
V
E
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
S438
L
P
L
N
F
L
G
S
V
Y
R
E
T
I
Q
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
E407
K
Q
S
L
I
D
M
E
T
L
F
K
L
R
K
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
N424
L
D
M
E
T
L
F
N
L
Q
K
V
N
V
T
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
N.A.
86.6
N.A.
46.6
0
0
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
73.3
13.3
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
0
0
0
0
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
74
0
0
0
7
7
0
0
0
0
0
60
7
7
% D
% Glu:
0
0
0
7
0
0
0
7
0
0
7
7
7
0
0
% E
% Phe:
0
0
0
0
14
0
74
0
0
0
7
7
0
0
0
% F
% Gly:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
54
0
0
0
7
7
0
0
7
0
0
0
0
7
0
% I
% Lys:
7
7
0
0
0
7
0
7
0
0
54
7
0
0
20
% K
% Leu:
20
7
14
7
7
67
0
0
74
67
0
0
7
7
0
% L
% Met:
0
0
74
0
0
14
7
7
0
7
7
0
0
0
7
% M
% Asn:
0
0
0
60
0
0
0
14
0
0
7
0
7
0
0
% N
% Pro:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
7
0
0
0
0
0
7
7
0
0
0
0
20
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
7
0
0
7
27
% R
% Ser:
7
0
7
0
0
0
0
7
0
0
14
0
0
7
7
% S
% Thr:
0
0
0
7
67
0
0
60
7
7
0
0
14
54
7
% T
% Val:
14
0
0
0
0
0
0
0
7
7
0
74
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _