Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB7 All Species: 16.97
Human Site: T51 Identified Species: 26.67
UniProt: O75027 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75027 NP_004290.2 752 82641 T51 H Q L G A L G T A R A Y Q I P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097352 753 82871 T51 H Q L G A L G T A R A Y Q Q I
Dog Lupus familis XP_549087 752 82813 T51 R Q L R A S G T A R I S Q I P
Cat Felis silvestris
Mouse Mus musculus Q61102 752 82576 S51 S Q R G A S G S A R L S Q T T
Rat Rattus norvegicus Q704E8 752 82539 S51 Y Q S G A S G S A R L S Q T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506747 870 95638 D170 G L V G R V L D S I P P Q V Q
Chicken Gallus gallus XP_420301 742 81302 K51 G T V P P I R K R R S W Q S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694879 743 82284 S52 E R N T Y L L S D P S R E S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728642 743 80448 K58 N S S D A K R K K I T P F T P
Honey Bee Apis mellifera XP_396202 744 83257 S62 T F G I R C C S R N V I D H T
Nematode Worm Caenorhab. elegans NP_001021830 704 77438 V50 L S K N K R A V V Q V F T R T
Sea Urchin Strong. purpuratus XP_001187214 731 80523 T52 H T D V R R E T T R T Y T H K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVM1 728 80402 I52 N Y I R R N S I R T S P V I N
Baker's Yeast Sacchar. cerevisiae P40416 690 77504 F44 S T Q R P L L F N S A V N L W
Red Bread Mold Neurospora crassa Q7RX59 716 78739 T51 A N L R A S F T T S S P R L F
Conservation
Percent
Protein Identity: 100 N.A. 99 92.6 N.A. 92.1 92.5 N.A. 73.7 78.8 N.A. 74.4 N.A. 51.5 53.1 49.8 54.6
Protein Similarity: 100 N.A. 99.4 94.9 N.A. 95.7 95.6 N.A. 79.1 87.2 N.A. 85.9 N.A. 68.4 70.4 68.2 69.9
P-Site Identity: 100 N.A. 86.6 66.6 N.A. 46.6 46.6 N.A. 13.3 13.3 N.A. 6.6 N.A. 13.3 0 0 26.6
P-Site Similarity: 100 N.A. 86.6 66.6 N.A. 53.3 60 N.A. 40 40 N.A. 33.3 N.A. 20 6.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 46.9 42.5 45
Protein Similarity: N.A. N.A. N.A. 63.4 61.9 64.2
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 20
P-Site Similarity: N.A. N.A. N.A. 26.6 20 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 47 0 7 0 34 0 20 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 0 0 7 7 0 0 0 7 0 0 % D
% Glu: 7 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % E
% Phe: 0 7 0 0 0 0 7 7 0 0 0 7 7 0 7 % F
% Gly: 14 0 7 34 0 0 34 0 0 0 0 0 0 0 0 % G
% His: 20 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % H
% Ile: 0 0 7 7 0 7 0 7 0 14 7 7 0 20 7 % I
% Lys: 0 0 7 0 7 7 0 14 7 0 0 0 0 0 7 % K
% Leu: 7 7 27 0 0 27 20 0 0 0 14 0 0 14 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 14 7 7 7 0 7 0 0 7 7 0 0 7 0 7 % N
% Pro: 0 0 0 7 14 0 0 0 0 7 7 27 0 0 20 % P
% Gln: 0 34 7 0 0 0 0 0 0 7 0 0 47 7 7 % Q
% Arg: 7 7 7 27 27 14 14 0 20 47 0 7 7 7 0 % R
% Ser: 14 14 14 0 0 27 7 27 7 14 27 20 0 14 7 % S
% Thr: 7 20 0 7 0 0 0 34 14 7 14 0 14 20 27 % T
% Val: 0 0 14 7 0 7 0 7 7 0 14 7 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % W
% Tyr: 7 7 0 0 7 0 0 0 0 0 0 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _