Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB7 All Species: 11.21
Human Site: T65 Identified Species: 17.62
UniProt: O75027 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75027 NP_004290.2 752 82641 T65 P E S L K S I T W Q R L G K G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097352 753 82871 I65 I P E S L K S I T W Q R L G K
Dog Lupus familis XP_549087 752 82813 T65 P E S L R Y T T W Q R L G K G
Cat Felis silvestris
Mouse Mus musculus Q61102 752 82576 T65 T E S L R N T T Q Q R W G K D
Rat Rattus norvegicus Q704E8 752 82539 T65 T E S L R N S T Q Q R W E K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506747 870 95638 F184 Q W L D R A R F R D G F W R A
Chicken Gallus gallus XP_420301 742 81302 P65 L M G G H S R P L L E I S A I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694879 743 82284 G66 S T W A N N R G Q N S Q Q I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728642 743 80448 L72 P T P G S K L L G G V F G K K
Honey Bee Apis mellifera XP_396202 744 83257 L76 T Q K K K N I L Q S K S I V T
Nematode Worm Caenorhab. elegans NP_001021830 704 77438 S64 T C F H P G A S S Q V P L Q A
Sea Urchin Strong. purpuratus XP_001187214 731 80523 P66 K K S D L D N P Y W Q Q K K I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVM1 728 80402 S66 N A F L S D N S P S P S P S P
Baker's Yeast Sacchar. cerevisiae P40416 690 77504 I58 W N Q A Q K D I T H K K S V E
Red Bread Mold Neurospora crassa Q7RX59 716 78739 K65 F A P N G S A K D E S K P A V
Conservation
Percent
Protein Identity: 100 N.A. 99 92.6 N.A. 92.1 92.5 N.A. 73.7 78.8 N.A. 74.4 N.A. 51.5 53.1 49.8 54.6
Protein Similarity: 100 N.A. 99.4 94.9 N.A. 95.7 95.6 N.A. 79.1 87.2 N.A. 85.9 N.A. 68.4 70.4 68.2 69.9
P-Site Identity: 100 N.A. 0 80 N.A. 53.3 46.6 N.A. 0 6.6 N.A. 0 N.A. 20 13.3 6.6 13.3
P-Site Similarity: 100 N.A. 6.6 86.6 N.A. 66.6 60 N.A. 20 13.3 N.A. 6.6 N.A. 26.6 33.3 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. 46.9 42.5 45
Protein Similarity: N.A. N.A. N.A. 63.4 61.9 64.2
P-Site Identity: N.A. N.A. N.A. 6.6 0 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 14 0 7 14 0 0 0 0 0 0 14 14 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 14 0 14 7 0 7 7 0 0 0 0 7 % D
% Glu: 0 27 7 0 0 0 0 0 0 7 7 0 7 0 7 % E
% Phe: 7 0 14 0 0 0 0 7 0 0 0 14 0 0 0 % F
% Gly: 0 0 7 14 7 7 0 7 7 7 7 0 27 7 14 % G
% His: 0 0 0 7 7 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 14 14 0 0 0 7 7 7 14 % I
% Lys: 7 7 7 7 14 20 0 7 0 0 14 14 7 40 14 % K
% Leu: 7 0 7 34 14 0 7 14 7 7 0 14 14 0 7 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 7 7 27 14 0 0 7 0 0 0 0 7 % N
% Pro: 20 7 14 0 7 0 0 14 7 0 7 7 14 0 7 % P
% Gln: 7 7 7 0 7 0 0 0 27 34 14 14 7 7 0 % Q
% Arg: 0 0 0 0 27 0 20 0 7 0 27 7 0 7 0 % R
% Ser: 7 0 34 7 14 20 14 14 7 14 14 14 14 7 0 % S
% Thr: 27 14 0 0 0 0 14 27 14 0 0 0 0 0 7 % T
% Val: 0 0 0 0 0 0 0 0 0 0 14 0 0 14 7 % V
% Trp: 7 7 7 0 0 0 0 0 14 14 0 14 7 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _