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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
27.27
Human Site:
T707
Identified Species:
42.86
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
T707
I
Y
S
E
M
W
H
T
Q
S
S
R
V
Q
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
T708
I
Y
S
E
M
W
H
T
Q
S
S
R
V
Q
N
Dog
Lupus familis
XP_549087
752
82813
T707
I
Y
S
E
M
W
H
T
Q
S
S
R
V
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
T707
I
Y
T
E
M
W
H
T
Q
S
N
R
V
Q
N
Rat
Rattus norvegicus
Q704E8
752
82539
T707
I
Y
S
E
M
W
H
T
Q
S
T
R
I
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
A826
I
Y
S
E
M
W
H
A
Q
S
S
R
A
L
S
Chicken
Gallus gallus
XP_420301
742
81302
T696
L
Y
Y
E
M
W
H
T
Q
S
S
K
V
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
T698
L
Y
A
N
L
W
N
T
Q
N
S
R
I
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
T702
G
R
V
G
E
R
G
T
H
S
E
L
L
R
Q
Honey Bee
Apis mellifera
XP_396202
744
83257
E703
L
D
N
G
S
L
I
E
K
G
T
H
D
C
L
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
L662
D
L
L
A
V
D
G
L
Y
A
Q
L
W
K
S
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
H689
I
G
E
R
G
K
H
H
Q
L
L
A
D
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
D681
L
T
T
A
M
Q
C
D
E
I
V
V
L
E
N
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
R649
I
I
V
L
D
N
G
R
V
R
E
E
G
K
H
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
H674
R
V
A
E
Q
G
T
H
R
E
L
M
E
R
N
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
73.3
73.3
N.A.
40
N.A.
13.3
0
0
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
80
86.6
N.A.
86.6
N.A.
26.6
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
0
0
0
7
0
7
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% C
% Asp:
7
7
0
0
7
7
0
7
0
0
0
0
14
0
0
% D
% Glu:
0
0
7
54
7
0
0
7
7
7
14
7
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
14
7
7
20
0
0
7
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
54
14
7
0
0
7
0
0
7
% H
% Ile:
54
7
0
0
0
0
7
0
0
7
0
0
14
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
7
0
0
7
0
14
0
% K
% Leu:
27
7
7
7
7
7
0
7
0
7
14
14
14
20
7
% L
% Met:
0
0
0
0
54
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
7
0
7
7
0
0
7
7
0
0
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
0
0
60
0
7
0
0
34
7
% Q
% Arg:
7
7
0
7
0
7
0
7
7
7
0
47
0
14
0
% R
% Ser:
0
0
34
0
7
0
0
0
0
54
40
0
0
0
20
% S
% Thr:
0
7
14
0
0
0
7
54
0
0
14
0
0
7
0
% T
% Val:
0
7
14
0
7
0
0
0
7
0
7
7
34
0
0
% V
% Trp:
0
0
0
0
0
54
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
54
7
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _