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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
45.76
Human Site:
Y345
Identified Species:
71.9
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
Y345
L
N
Y
E
T
V
K
Y
F
N
N
E
R
Y
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
Y346
L
N
Y
E
T
V
K
Y
F
N
N
E
R
Y
E
Dog
Lupus familis
XP_549087
752
82813
Y345
L
N
Y
E
T
V
K
Y
F
N
N
E
N
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
Y345
L
N
Y
E
T
V
K
Y
F
N
N
E
K
Y
E
Rat
Rattus norvegicus
Q704E8
752
82539
Y345
L
N
Y
E
T
V
K
Y
F
N
N
E
K
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
Y464
L
N
Y
E
T
V
K
Y
F
N
N
E
K
Y
E
Chicken
Gallus gallus
XP_420301
742
81302
Y334
L
N
Y
E
T
V
K
Y
F
N
N
E
K
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
Y336
L
N
Y
E
T
V
K
Y
F
N
N
E
K
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
Y358
I
N
Y
E
T
V
K
Y
F
N
N
E
K
Y
E
Honey Bee
Apis mellifera
XP_396202
744
83257
Y357
A
I
D
S
L
I
N
Y
E
T
V
K
Y
F
N
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
E315
Y
F
N
N
E
K
F
E
A
D
R
Y
D
H
F
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
Y343
I
N
Y
E
T
V
K
Y
F
N
N
E
K
W
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
D337
A
M
N
K
A
D
N
D
A
S
T
R
A
I
D
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
E306
L
D
S
L
I
N
F
E
A
V
K
Y
F
N
N
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
Y323
I
N
Y
E
A
V
K
Y
F
N
N
E
A
Y
E
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
86.6
6.6
0
80
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
26.6
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
80
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
14
0
0
0
20
0
0
0
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
7
0
7
0
7
0
0
7
0
7
% D
% Glu:
0
0
0
74
7
0
0
14
7
0
0
74
0
0
74
% E
% Phe:
0
7
0
0
0
0
14
0
74
0
0
0
7
7
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
20
7
0
0
7
7
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
7
0
7
74
0
0
0
7
7
47
0
0
% K
% Leu:
60
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
74
14
7
0
7
14
0
0
74
74
0
7
7
14
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
7
14
0
0
% R
% Ser:
0
0
7
7
0
0
0
0
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
0
67
0
0
0
0
7
7
0
0
0
0
% T
% Val:
0
0
0
0
0
74
0
0
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
7
0
74
0
0
0
0
80
0
0
0
14
7
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _