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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
36.67
Human Site:
Y522
Identified Species:
57.62
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
Y522
V
R
L
L
F
R
F
Y
E
P
Q
K
G
S
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
Y523
V
R
L
L
F
R
F
Y
E
P
Q
K
G
S
I
Dog
Lupus familis
XP_549087
752
82813
Y522
V
R
L
L
F
R
F
Y
E
P
Q
K
G
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
Y522
V
R
L
L
F
R
F
Y
E
P
Q
K
G
S
I
Rat
Rattus norvegicus
Q704E8
752
82539
Y522
V
R
L
L
F
R
F
Y
E
P
Q
K
G
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
Y641
V
R
L
L
F
R
F
Y
E
P
Q
Q
G
S
I
Chicken
Gallus gallus
XP_420301
742
81302
Y511
V
R
L
L
F
R
F
Y
E
P
Q
K
G
N
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
Y513
V
R
L
L
F
R
F
Y
E
P
Q
Q
G
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
F535
V
R
L
L
F
R
F
F
E
P
N
S
G
K
V
Honey Bee
Apis mellifera
XP_396202
744
83257
L534
G
K
T
T
L
V
R
L
L
Y
R
F
F
E
P
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
V492
Y
D
T
E
S
G
N
V
R
I
N
G
L
E
T
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
Y520
V
R
L
L
F
R
F
Y
D
P
D
A
G
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
S514
S
V
A
I
V
G
T
S
G
S
G
K
S
T
I
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
F483
S
T
I
L
K
L
V
F
R
F
Y
D
P
E
S
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
D500
R
L
L
F
R
F
Y
D
P
Q
K
G
A
I
Y
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
66.6
0
0
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
80
13.3
0
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
7
7
0
7
7
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
60
0
0
0
0
20
0
% E
% Phe:
0
0
0
7
67
7
67
14
0
7
0
7
7
0
0
% F
% Gly:
7
0
0
0
0
14
0
0
7
0
7
14
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
0
0
0
0
7
0
0
0
7
60
% I
% Lys:
0
7
0
0
7
0
0
0
0
0
7
47
0
7
0
% K
% Leu:
0
7
74
74
7
7
0
7
7
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
14
0
0
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
67
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
54
14
0
0
0
% Q
% Arg:
7
67
0
0
7
67
7
0
14
0
7
0
0
7
0
% R
% Ser:
14
0
0
0
7
0
0
7
0
7
0
7
7
34
7
% S
% Thr:
0
7
14
7
0
0
7
0
0
0
0
0
0
7
7
% T
% Val:
67
7
0
0
7
7
7
7
0
0
0
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
60
0
7
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _