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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB7
All Species:
13.94
Human Site:
Y55
Identified Species:
21.9
UniProt:
O75027
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75027
NP_004290.2
752
82641
Y55
A
L
G
T
A
R
A
Y
Q
I
P
E
S
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097352
753
82871
Y55
A
L
G
T
A
R
A
Y
Q
Q
I
P
E
S
L
Dog
Lupus familis
XP_549087
752
82813
S55
A
S
G
T
A
R
I
S
Q
I
P
E
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61102
752
82576
S55
A
S
G
S
A
R
L
S
Q
T
T
E
S
L
R
Rat
Rattus norvegicus
Q704E8
752
82539
S55
A
S
G
S
A
R
L
S
Q
T
T
E
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506747
870
95638
P174
R
V
L
D
S
I
P
P
Q
V
Q
W
L
D
R
Chicken
Gallus gallus
XP_420301
742
81302
W55
P
I
R
K
R
R
S
W
Q
S
L
M
G
G
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694879
743
82284
R56
Y
L
L
S
D
P
S
R
E
S
S
T
W
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728642
743
80448
P62
A
K
R
K
K
I
T
P
F
T
P
T
P
G
S
Honey Bee
Apis mellifera
XP_396202
744
83257
I66
R
C
C
S
R
N
V
I
D
H
T
Q
K
K
K
Nematode Worm
Caenorhab. elegans
NP_001021830
704
77438
F54
K
R
A
V
V
Q
V
F
T
R
T
C
F
H
P
Sea Urchin
Strong. purpuratus
XP_001187214
731
80523
Y56
R
R
E
T
T
R
T
Y
T
H
K
K
S
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVM1
728
80402
P56
R
N
S
I
R
T
S
P
V
I
N
A
F
L
S
Baker's Yeast
Sacchar. cerevisiae
P40416
690
77504
V48
P
L
L
F
N
S
A
V
N
L
W
N
Q
A
Q
Red Bread Mold
Neurospora crassa
Q7RX59
716
78739
P55
A
S
F
T
T
S
S
P
R
L
F
A
P
N
G
Conservation
Percent
Protein Identity:
100
N.A.
99
92.6
N.A.
92.1
92.5
N.A.
73.7
78.8
N.A.
74.4
N.A.
51.5
53.1
49.8
54.6
Protein Similarity:
100
N.A.
99.4
94.9
N.A.
95.7
95.6
N.A.
79.1
87.2
N.A.
85.9
N.A.
68.4
70.4
68.2
69.9
P-Site Identity:
100
N.A.
60
73.3
N.A.
53.3
53.3
N.A.
6.6
13.3
N.A.
6.6
N.A.
13.3
6.6
0
26.6
P-Site Similarity:
100
N.A.
60
80
N.A.
66.6
66.6
N.A.
33.3
33.3
N.A.
26.6
N.A.
13.3
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
42.5
45
Protein Similarity:
N.A.
N.A.
N.A.
63.4
61.9
64.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
7
0
34
0
20
0
0
0
0
14
0
14
0
% A
% Cys:
0
7
7
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
7
0
0
0
0
14
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
0
0
27
7
0
0
% E
% Phe:
0
0
7
7
0
0
0
7
7
0
7
0
14
0
0
% F
% Gly:
0
0
34
0
0
0
0
0
0
0
0
0
7
14
7
% G
% His:
0
0
0
0
0
0
0
0
0
14
0
0
0
7
7
% H
% Ile:
0
7
0
7
0
14
7
7
0
20
7
0
0
0
0
% I
% Lys:
7
7
0
14
7
0
0
0
0
0
7
7
7
7
14
% K
% Leu:
0
27
20
0
0
0
14
0
0
14
7
0
7
34
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
7
0
0
7
7
0
0
7
0
7
7
0
7
7
% N
% Pro:
14
0
0
0
0
7
7
27
0
0
20
7
14
0
7
% P
% Gln:
0
0
0
0
0
7
0
0
47
7
7
7
7
0
7
% Q
% Arg:
27
14
14
0
20
47
0
7
7
7
0
0
0
0
27
% R
% Ser:
0
27
7
27
7
14
27
20
0
14
7
0
34
7
14
% S
% Thr:
0
0
0
34
14
7
14
0
14
20
27
14
0
0
0
% T
% Val:
0
7
0
7
7
0
14
7
7
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
7
7
7
0
0
% W
% Tyr:
7
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _