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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MITF
All Species:
13.64
Human Site:
T352
Identified Species:
50
UniProt:
O75030
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75030
NP_000239.1
526
58795
T352
D
M
R
W
N
K
G
T
I
L
K
A
S
V
D
Chimpanzee
Pan troglodytes
A2T713
347
38902
K207
R
E
L
E
H
R
Q
K
K
L
E
Q
A
N
R
Rhesus Macaque
Macaca mulatta
XP_001086622
526
58747
T352
D
M
R
W
N
K
G
T
I
L
K
A
S
V
D
Dog
Lupus familis
XP_863779
580
61999
T393
E
M
R
W
N
K
G
T
I
L
K
A
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q08874
526
58609
T352
D
M
R
W
N
K
G
T
I
L
K
A
S
V
D
Rat
Rattus norvegicus
Q63302
317
35156
Q177
A
R
E
L
E
H
R
Q
K
K
L
E
H
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5XFQ6
377
42496
K237
R
E
L
E
H
R
Q
K
K
L
E
H
A
N
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
99.8
47.2
N.A.
95.2
33.8
N.A.
N.A.
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49
99.8
60.1
N.A.
96.9
44.4
N.A.
N.A.
53
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
6.6
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
0
0
0
0
58
29
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% D
% Glu:
15
29
15
29
15
0
0
0
0
0
29
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
29
15
0
0
0
0
0
15
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
58
0
29
43
15
58
0
0
0
0
% K
% Leu:
0
0
29
15
0
0
0
0
0
86
15
0
0
0
0
% L
% Met:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
58
0
0
0
0
0
0
0
0
29
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
29
15
0
0
0
15
0
0
0
% Q
% Arg:
29
15
58
0
0
29
15
0
0
0
0
0
0
0
29
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% S
% Thr:
0
0
0
0
0
0
0
58
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% V
% Trp:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _