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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF21B
All Species:
9.39
Human Site:
S623
Identified Species:
17.22
UniProt:
O75037
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75037
NP_060066.2
1637
182662
S623
E
S
L
V
D
S
D
S
D
P
E
E
K
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099469
1663
184637
E711
E
E
E
G
R
E
D
E
D
E
D
S
G
S
E
Dog
Lupus familis
XP_547366
1470
163982
S557
S
P
Y
S
L
G
A
S
P
A
A
A
A
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXL1
1668
186145
S624
E
S
L
V
D
S
D
S
D
P
E
E
K
E
V
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
Q511
E
E
L
R
R
Q
M
Q
L
M
A
Q
E
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521746
1544
171654
S544
E
S
L
V
D
S
D
S
D
P
E
E
K
E
V
Chicken
Gallus gallus
Q90640
1225
138905
P342
A
R
K
I
K
N
K
P
I
V
N
V
D
P
Q
Frog
Xenopus laevis
Q91784
1226
138905
V343
K
I
K
N
K
P
I
V
N
T
D
P
Q
A
A
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
Q480
S
T
A
L
K
R
R
Q
A
V
L
N
N
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609398
1048
119019
D165
Y
I
E
L
Y
N
E
D
I
F
D
L
L
D
P
Honey Bee
Apis mellifera
XP_394542
1442
161348
D558
D
S
D
R
K
E
E
D
E
E
E
A
A
M
G
Nematode Worm
Caenorhab. elegans
P46873
699
78760
Sea Urchin
Strong. purpuratus
P46871
742
84184
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.2
82.2
N.A.
94.5
23.3
N.A.
86
27.8
27.3
24
N.A.
32.1
41.9
22.3
23.6
Protein Similarity:
100
N.A.
93.3
84.6
N.A.
96.3
41.7
N.A.
90.2
44.7
43.6
42.4
N.A.
45.4
58.7
30.9
33.6
P-Site Identity:
100
N.A.
20
6.6
N.A.
100
13.3
N.A.
100
0
0
0
N.A.
0
13.3
0
0
P-Site Similarity:
100
N.A.
26.6
6.6
N.A.
100
26.6
N.A.
100
13.3
26.6
20
N.A.
33.3
33.3
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
0
8
8
16
16
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
24
0
31
16
31
0
24
0
8
8
8
% D
% Glu:
39
16
16
0
0
16
16
8
8
16
31
24
8
24
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
8
0
0
8
0
16
0
0
0
0
0
0
% I
% Lys:
8
0
16
0
31
0
8
0
0
0
0
0
24
0
8
% K
% Leu:
0
0
31
16
8
0
0
0
8
0
8
8
8
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
16
0
0
8
0
8
8
8
0
0
% N
% Pro:
0
8
0
0
0
8
0
8
8
24
0
8
0
8
8
% P
% Gln:
0
0
0
0
0
8
0
16
0
0
0
8
8
8
8
% Q
% Arg:
0
8
0
16
16
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
16
31
0
8
0
24
0
31
0
0
0
8
0
16
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
24
0
0
0
8
0
16
0
8
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _