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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF21B All Species: 11.52
Human Site: T357 Identified Species: 21.11
UniProt: O75037 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75037 NP_060066.2 1637 182662 T357 S D R D F M E T L N T L K Y A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099469 1663 184637 T460 S D R D F M E T L N T L K Y A
Dog Lupus familis XP_547366 1470 163982 E329 A T G E R A K E G I S I N C G
Cat Felis silvestris
Mouse Mus musculus Q9QXL1 1668 186145 T358 S D R D F M E T L N T L K Y A
Rat Rattus norvegicus Q7M6Z5 1394 158861 S289 G D P R R K S S H V P Y R D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521746 1544 171654 Y322 L Q M E L L E Y K T G K R V L
Chicken Gallus gallus Q90640 1225 138905 K120 G V I P R V I K L L F K E K E
Frog Xenopus laevis Q91784 1226 138905 L121 I P R T V I A L F R E I H Q R
Zebra Danio Brachydanio rerio Q58G59 1363 154819 L258 L A G S E R I L K T G N T G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609398 1048 119019
Honey Bee Apis mellifera XP_394542 1442 161348 C335 S Q T V M I A C V S P S D R D
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46871 742 84184
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93.2 82.2 N.A. 94.5 23.3 N.A. 86 27.8 27.3 24 N.A. 32.1 41.9 22.3 23.6
Protein Similarity: 100 N.A. 93.3 84.6 N.A. 96.3 41.7 N.A. 90.2 44.7 43.6 42.4 N.A. 45.4 58.7 30.9 33.6
P-Site Identity: 100 N.A. 100 0 N.A. 100 13.3 N.A. 6.6 6.6 6.6 0 N.A. 0 6.6 0 0
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 26.6 N.A. 26.6 20 20 0 N.A. 0 26.6 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 16 0 0 0 0 0 0 0 31 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % C
% Asp: 0 31 0 24 0 0 0 0 0 0 0 0 8 8 8 % D
% Glu: 0 0 0 16 8 0 31 8 0 0 8 0 8 0 16 % E
% Phe: 0 0 0 0 24 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 16 0 16 0 0 0 0 0 8 0 16 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 8 0 8 0 0 16 16 0 0 8 0 16 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 8 16 0 0 16 24 8 0 % K
% Leu: 16 0 0 0 8 8 0 16 31 8 0 24 0 0 8 % L
% Met: 0 0 8 0 8 24 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 24 0 8 8 0 0 % N
% Pro: 0 8 8 8 0 0 0 0 0 0 16 0 0 0 0 % P
% Gln: 0 16 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 31 8 24 8 0 0 0 8 0 0 16 8 8 % R
% Ser: 31 0 0 8 0 0 8 8 0 8 8 8 0 0 0 % S
% Thr: 0 8 8 8 0 0 0 24 0 16 24 0 8 0 0 % T
% Val: 0 8 0 8 8 8 0 0 8 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 8 0 24 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _